Direct Meds vs Sesame Care: Which Is Better?
Head-to-head comparison of Direct Meds and Sesame Care based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.
Our Verdict
Sesame Care scores higher overall in our independent evaluation (74/100 vs 73.5/100), leading on trust & safety, product range, reputation. Direct Meds comes out ahead on value, experience.
Cash-pay pharmacy and telehealth combo focused on transparent pricing and no-surprise billing.
Visit Direct MedsPay-per-visit marketplace connecting patients with licensed providers — no subscriptions, transparent per-visit pricing.
Visit Sesame CareScore Breakdown
| Dimension | Direct Meds | Sesame Care |
|---|---|---|
| Overall Score | 73.5/100 | 74/100 ✓ |
| Trust & Safety30% | 72/100 | 75/100 ✓ |
| Value25% | 82/100 ✓ | 80/100 |
| Experience20% | 74/100 ✓ | 70/100 |
| Product Range15% | 65/100 | 70/100 ✓ |
| Reputation10% | 68/100 | 70/100 ✓ |
At a Glance
| Founded | 2021 | 2019 |
| Headquarters | Miami, FL | New York, NY |
| Publicly traded | No | No |
| Treatment categories | 3 | 6 |
| Treatments listed | 5 | 5 |
| Starting price | $179/mo | $34/mo |
Pricing Where They Compete
Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.
| Category | Direct Meds | Sesame Care |
|---|---|---|
| Weight Loss / GLP-1 | $179–$249 Compounded Semaglutide (sublingual) | $59–$99 Weight Loss Program (subscription) |
| Men's Health | $199–$249 NAD+ Injections | — |
Direct Meds
Sesame Care
Direct Meds vs Sesame Care — FAQ
Is Direct Meds better than Sesame Care?
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Sesame Care scores higher overall in our independent evaluation (74/100 vs 73.5/100), leading on trust & safety, product range, reputation. Direct Meds comes out ahead on value, experience.
Is Direct Meds or Sesame Care cheaper?
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Sesame Care has the lower starting price (from $34/mo vs $179/mo for Direct Meds). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.
What do Direct Meds and Sesame Care both offer?
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Both platforms treat Weight Loss / GLP-1, Men's Health. Direct Meds covers 3 treatment categories total and Sesame Care covers 6.
Still deciding?