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PlushCare vs TrimRx: Which Is Better?

Head-to-head comparison of PlushCare and TrimRx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

PlushCare scores higher overall in our independent evaluation (68.3/100 vs 52/100), leading on trust & safety, experience, product range, reputation. TrimRx comes out ahead on value.

68

PlushCare is a virtual primary-care membership service that layers weight-loss visits and branded GLP-1 prescriptions onto its core telehealth offering, rather than running a dedicated compounded-GLP-1 program.

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52
TrimRx
Below Average

San Diego-based GLP-1 weight loss telehealth offering compounded semaglutide and tirzepatide at $179-349/month.

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Score Breakdown

DimensionPlushCareTrimRx
Overall Score68.3/100 ✓52/100
Trust & Safety30%78/100 ✓55/100
Value25%62/10070/100 ✓
Experience20%62/100 ✓45/100
Product Range15%65/100 ✓30/100
Reputation10%72/100 ✓45/100

At a Glance

Founded20142024
HeadquartersSan Francisco, CASan Diego, CA
Publicly tradedNoNo
Treatment categories21
Treatments listed36
Starting price$20/mo$179/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryPlushCareTrimRx
Weight Loss / GLP-1$650–$1100
Branded GLP-1 Prescription (Wegovy, Saxenda)
$179–$329
Compounded Semaglutide (Oral/Sublingual)

PlushCare

+Low $19.99/mo membership with first month free, and insurance-eligible visits as low as a $30 copay
+Accepts major insurance plans (Aetna, Cigna, Humana), broader than most single-purpose GLP-1 telehealth startups
+Physician-led primary care model covers ongoing and chronic care beyond a single weight-loss funnel
−Branded GLP-1 medication (Zepbound, Wegovy) is billed separately at the pharmacy — without insurance coverage this can run roughly $1,000+/month, dwarfing the low membership fee
−No compounded GLP-1 option, so cash-pay patients without drug coverage face full retail brand pricing
−Trustpilot pattern of unexpected recurring membership charges and difficulty cancelling
Read the full PlushCare review →

TrimRx

+70-85% savings vs brand-name GLP-1s: semaglutide at $199/mo vs $1,000+ retail
+Not included in FDA's 2025 warning letter wave — clean regulatory record
+Multiple delivery formats: injectable, oral tablet, and sublingual drops
−Cancellation difficulties: long phone waits, reports of being hung up on; dedicated JoinChargeback page exists
−Strict no-refund policy once medical intake is submitted, even before medication ships
−Very young company (founded June 2024) — less than 2 years old
Read the full TrimRx review →

PlushCare vs TrimRx — FAQ

Is PlushCare better than TrimRx?

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PlushCare scores higher overall in our independent evaluation (68.3/100 vs 52/100), leading on trust & safety, experience, product range, reputation. TrimRx comes out ahead on value.

Is PlushCare or TrimRx cheaper?

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PlushCare has the lower starting price (from $20/mo vs $179/mo for TrimRx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do PlushCare and TrimRx both offer?

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Both platforms treat Weight Loss / GLP-1. PlushCare covers 2 treatment categories total and TrimRx covers 1.

Still deciding?

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