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AgelessRx vs Calibrate: Which Is Better?

Head-to-head comparison of AgelessRx and Calibrate based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

AgelessRx scores higher overall in our independent evaluation (73.4/100 vs 66.9/100), leading on value, product range, reputation. Calibrate comes out ahead on trust & safety, experience.

73

AgelessRx is an Ann Arbor-based longevity telehealth company that prescribes rapamycin, metformin, low-dose naltrexone and NAD+, and also sells compounded and branded GLP-1s.

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67

Calibrate is a year-long metabolic-reset program pairing coaching and biomarker tracking with insurance-navigated branded GLP-1 prescribing — built for members who already have GLP-1 coverage, not cash-pay patients.

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Score Breakdown

DimensionAgelessRxCalibrate
Overall Score73.4/100 ✓66.9/100
Trust & Safety30%72/10076/100 ✓
Value25%74/100 ✓58/100
Experience20%70/10072/100 ✓
Product Range15%82/100 ✓60/100
Reputation10%70/100 ✓62/100

At a Glance

Founded20192019
HeadquartersAnn Arbor, MINew York, NY
Publicly tradedNoNo
Treatment categories41
Treatments listed142
Starting price$25/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryAgelessRxCalibrate
Weight Loss / GLP-1$99
Microdosing Semaglutide
$25–$1350
Insurance-Navigated Branded GLP-1

AgelessRx

+Deepest longevity formulary we track: rapamycin ($65/mo), metformin and LDN ($25/mo), NAD+, sermorelin, glutathione and B12
+Research-led: publishes a named medical director and runs its own decentralised trials (e.g. PEARL rapamycin study)
+Low entry prices with video visits and shipping included and no separate membership fee
−No consolidated price list; GLP-1 and NAD+ prices vary widely by plan length ($79 vs $235/mo reported for NAD+ injections)
−Headline microdosed tirzepatide price ($159/mo) requires a four-month plan billed upfront (~$636)
−Reviewers report slow support replies, billing/card-decline errors and heavy marketing email
Read the full AgelessRx review →

Calibrate

+Comprehensive year-long program combining 1:1 coaching, biomarker/lab review, and a connected smart scale alongside GLP-1 prescribing
+Insurance-navigation support aims to get members GLP-1 medication near a $25/month copay when commercial coverage applies
+Strong Trustpilot rating (4.5/5, ~1,200 reviews) with many members reporting 40-70+ lb losses
−Poor fit and high cost for cash-pay patients without GLP-1 insurance coverage — medication bills separately and can approach full brand retail (roughly $1,000+/month) if a plan doesn't cover it
−$199/month program fee requires a 3-month minimum commitment ($597) before month-to-month conversion
−Reports of 3+ week waits for medication-dose changes and inconsistent coach assignment session-to-session
Read the full Calibrate review →

AgelessRx vs Calibrate — FAQ

Is AgelessRx better than Calibrate?

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AgelessRx scores higher overall in our independent evaluation (73.4/100 vs 66.9/100), leading on value, product range, reputation. Calibrate comes out ahead on trust & safety, experience.

Is AgelessRx or Calibrate cheaper?

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Their entry prices are similar — both start around $25/mo. Real cost depends on the specific treatment: compare the pricing tables on each review, since inclusions like consults, labs, and shipping differ.

What do AgelessRx and Calibrate both offer?

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Both platforms treat Weight Loss / GLP-1. AgelessRx covers 4 treatment categories total and Calibrate covers 1.

Still deciding?

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