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AgelessRx vs He & She MD: Which Is Better?

Head-to-head comparison of AgelessRx and He & She MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

AgelessRx scores higher overall in our independent evaluation (73.4/100 vs 65.3/100), leading on trust & safety, experience, reputation. He & She MD comes out ahead on product range.

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AgelessRx is an Ann Arbor-based longevity telehealth company that prescribes rapamycin, metformin, low-dose naltrexone and NAD+, and also sells compounded and branded GLP-1s.

Visit AgelessRx

He & She MD is a Newport Beach-based men's and women's telehealth brand covering GLP-1s, longevity injectables, HRT, testosterone, hair loss and ED, with the lowest prices tied to long prepaid terms.

Visit He & She MD

Score Breakdown

DimensionAgelessRxHe & She MD
Overall Score73.4/100 ✓65.3/100
Trust & Safety30%72/100 ✓58/100
Value25%74/10074/100
Experience20%70/100 ✓60/100
Product Range15%82/10084/100 ✓
Reputation10%70/100 ✓48/100

At a Glance

Founded20192025
HeadquartersAnn Arbor, MINewport Beach, CA
Publicly tradedNoNo
Treatment categories47
Treatments listed1413
Starting price$25/mo$60/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryAgelessRxHe & She MD
Longevity & Peptides$25
Metformin
$100–$149
Glutathione
Weight Loss / GLP-1$99
Microdosing Semaglutide
$99–$199
Compounded Semaglutide (injectable)
Hormone Therapy$50
Women's Hormone Care
$119
Testosterone (injection, gel, tablet)
Women's Health——

AgelessRx

+Deepest longevity formulary we track: rapamycin ($65/mo), metformin and LDN ($25/mo), NAD+, sermorelin, glutathione and B12
+Research-led: publishes a named medical director and runs its own decentralised trials (e.g. PEARL rapamycin study)
+Low entry prices with video visits and shipping included and no separate membership fee
−No consolidated price list; GLP-1 and NAD+ prices vary widely by plan length ($79 vs $235/mo reported for NAD+ injections)
−Headline microdosed tirzepatide price ($159/mo) requires a four-month plan billed upfront (~$636)
−Reviewers report slow support replies, billing/card-decline errors and heavy marketing email
Read the full AgelessRx review →

He & She MD

+Broad catalog covering compounded GLP-1s (injectable and oral), NAD+, sermorelin, glutathione, estradiol/progesterone HRT, testosterone, enclomiphene, hair loss and ED
+Names its dispensing pharmacies and the states where one partner cannot ship sterile compounds
+Low entry pricing on long terms: compounded semaglutide $99/mo on annual prepay, hair loss $79/mo, ED from $10/dose
−Site shows '4.8 Excellent' and 5.0 rating badges while its Trustpilot profile has zero reviews, so the ratings can't be verified
−Most headline prices require 3- to 12-month prepayment; month-to-month semaglutide is $199 and tirzepatide $299
−Platform terms allow a $15 fee per additional consult or lab-result interpretation on top of plan prices
Read the full He & She MD review →

AgelessRx vs He & She MD — FAQ

Is AgelessRx better than He & She MD?

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AgelessRx scores higher overall in our independent evaluation (73.4/100 vs 65.3/100), leading on trust & safety, experience, reputation. He & She MD comes out ahead on product range.

Is AgelessRx or He & She MD cheaper?

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AgelessRx has the lower starting price (from $25/mo vs $60/mo for He & She MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do AgelessRx and He & She MD both offer?

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Both platforms treat Longevity & Peptides, Weight Loss / GLP-1, Hormone Therapy, Women's Health. AgelessRx covers 4 treatment categories total and He & She MD covers 7.

Still deciding?