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AgelessRx vs PlushCare: Which Is Better?

Head-to-head comparison of AgelessRx and PlushCare based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

AgelessRx scores higher overall in our independent evaluation (73.4/100 vs 68.3/100), leading on value, experience, product range. PlushCare comes out ahead on trust & safety, reputation. PlushCare has the lower entry price (from $20/mo vs $25/mo), so the better value depends on which treatment you need.

73

AgelessRx is an Ann Arbor-based longevity telehealth company that prescribes rapamycin, metformin, low-dose naltrexone and NAD+, and also sells compounded and branded GLP-1s.

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68

PlushCare is a virtual primary-care membership service that layers weight-loss visits and branded GLP-1 prescriptions onto its core telehealth offering, rather than running a dedicated compounded-GLP-1 program.

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Score Breakdown

DimensionAgelessRxPlushCare
Overall Score73.4/100 ✓68.3/100
Trust & Safety30%72/10078/100 ✓
Value25%74/100 ✓62/100
Experience20%70/100 ✓62/100
Product Range15%82/100 ✓65/100
Reputation10%70/10072/100 ✓

At a Glance

Founded20192014
HeadquartersAnn Arbor, MISan Francisco, CA
Publicly tradedNoNo
Treatment categories42
Treatments listed143
Starting price$25/mo$20/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryAgelessRxPlushCare
Weight Loss / GLP-1$99
Microdosing Semaglutide
$650–$1100
Branded GLP-1 Prescription (Wegovy, Saxenda)

AgelessRx

+Deepest longevity formulary we track: rapamycin ($65/mo), metformin and LDN ($25/mo), NAD+, sermorelin, glutathione and B12
+Research-led: publishes a named medical director and runs its own decentralised trials (e.g. PEARL rapamycin study)
+Low entry prices with video visits and shipping included and no separate membership fee
−No consolidated price list; GLP-1 and NAD+ prices vary widely by plan length ($79 vs $235/mo reported for NAD+ injections)
−Headline microdosed tirzepatide price ($159/mo) requires a four-month plan billed upfront (~$636)
−Reviewers report slow support replies, billing/card-decline errors and heavy marketing email
Read the full AgelessRx review →

PlushCare

+Low $19.99/mo membership with first month free, and insurance-eligible visits as low as a $30 copay
+Accepts major insurance plans (Aetna, Cigna, Humana), broader than most single-purpose GLP-1 telehealth startups
+Physician-led primary care model covers ongoing and chronic care beyond a single weight-loss funnel
−Branded GLP-1 medication (Zepbound, Wegovy) is billed separately at the pharmacy — without insurance coverage this can run roughly $1,000+/month, dwarfing the low membership fee
−No compounded GLP-1 option, so cash-pay patients without drug coverage face full retail brand pricing
−Trustpilot pattern of unexpected recurring membership charges and difficulty cancelling
Read the full PlushCare review →

AgelessRx vs PlushCare — FAQ

Is AgelessRx better than PlushCare?

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AgelessRx scores higher overall in our independent evaluation (73.4/100 vs 68.3/100), leading on value, experience, product range. PlushCare comes out ahead on trust & safety, reputation. PlushCare has the lower entry price (from $20/mo vs $25/mo), so the better value depends on which treatment you need.

Is AgelessRx or PlushCare cheaper?

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PlushCare has the lower starting price (from $20/mo vs $25/mo for AgelessRx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do AgelessRx and PlushCare both offer?

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Both platforms treat Weight Loss / GLP-1. AgelessRx covers 4 treatment categories total and PlushCare covers 2.

Still deciding?

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