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AgelessRx vs ProlongMD: Which Is Better?

Head-to-head comparison of AgelessRx and ProlongMD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

AgelessRx scores higher overall in our independent evaluation (73.4/100 vs 60.1/100), leading on trust & safety, experience, product range, reputation.

73

AgelessRx is an Ann Arbor-based longevity telehealth company that prescribes rapamycin, metformin, low-dose naltrexone and NAD+, and also sells compounded and branded GLP-1s.

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60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD

Score Breakdown

DimensionAgelessRxProlongMD
Overall Score73.4/100 ✓60.1/100
Trust & Safety30%72/100 ✓52/100
Value25%74/10074/100
Experience20%70/100 ✓55/100
Product Range15%82/100 ✓70/100
Reputation10%70/100 ✓45/100

At a Glance

Founded20192025
HeadquartersAnn Arbor, MIPhoenix, AZ
Publicly tradedNoNo
Treatment categories48
Treatments listed1413
Starting price$25/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryAgelessRxProlongMD
Longevity & Peptides$25
Metformin
$179
Sermorelin
Weight Loss / GLP-1$99
Microdosing Semaglutide
$99–$119
Compounded Semaglutide/B12
Hormone Therapy$50
Women's Hormone Care
$89–$119
Testosterone Cypionate (200 mg/mL)
Women's Health—$33
Progesterone (oral)

AgelessRx

+Deepest longevity formulary we track: rapamycin ($65/mo), metformin and LDN ($25/mo), NAD+, sermorelin, glutathione and B12
+Research-led: publishes a named medical director and runs its own decentralised trials (e.g. PEARL rapamycin study)
+Low entry prices with video visits and shipping included and no separate membership fee
−No consolidated price list; GLP-1 and NAD+ prices vary widely by plan length ($79 vs $235/mo reported for NAD+ injections)
−Headline microdosed tirzepatide price ($159/mo) requires a four-month plan billed upfront (~$636)
−Reviewers report slow support replies, billing/card-decline errors and heavy marketing email
Read the full AgelessRx review →

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

AgelessRx vs ProlongMD — FAQ

Is AgelessRx better than ProlongMD?

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AgelessRx scores higher overall in our independent evaluation (73.4/100 vs 60.1/100), leading on trust & safety, experience, product range, reputation.

Is AgelessRx or ProlongMD cheaper?

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Their entry prices are similar — both start around $25/mo. Real cost depends on the specific treatment: compare the pricing tables on each review, since inclusions like consults, labs, and shipping differ.

What do AgelessRx and ProlongMD both offer?

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Both platforms treat Longevity & Peptides, Weight Loss / GLP-1, Hormone Therapy, Women's Health. AgelessRx covers 4 treatment categories total and ProlongMD covers 8.

Still deciding?

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