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AgelessRx vs RxSpan MD: Which Is Better?

Head-to-head comparison of AgelessRx and RxSpan MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

AgelessRx scores higher overall in our independent evaluation (73.4/100 vs 59.1/100), leading on trust & safety, value, experience, product range, reputation.

73

AgelessRx is an Ann Arbor-based longevity telehealth company that prescribes rapamycin, metformin, low-dose naltrexone and NAD+, and also sells compounded and branded GLP-1s.

Visit AgelessRx
59

RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

Visit RxSpan MD

Score Breakdown

DimensionAgelessRxRxSpan MD
Overall Score73.4/100 ✓59.1/100
Trust & Safety30%72/100 ✓60/100
Value25%74/100 ✓58/100
Experience20%70/100 ✓52/100
Product Range15%82/100 ✓78/100
Reputation10%70/100 ✓45/100

At a Glance

Founded20192026
HeadquartersAnn Arbor, MIBeverly Hills, CA
Publicly tradedNoNo
Treatment categories44
Treatments listed149
Starting price$25/mo$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryAgelessRxRxSpan MD
Longevity & Peptides$25
Metformin
$100–$200
Glutathione
Weight Loss / GLP-1$99
Microdosing Semaglutide
$249–$299
Compounded Semaglutide (injection or oral)

AgelessRx

+Deepest longevity formulary we track: rapamycin ($65/mo), metformin and LDN ($25/mo), NAD+, sermorelin, glutathione and B12
+Research-led: publishes a named medical director and runs its own decentralised trials (e.g. PEARL rapamycin study)
+Low entry prices with video visits and shipping included and no separate membership fee
−No consolidated price list; GLP-1 and NAD+ prices vary widely by plan length ($79 vs $235/mo reported for NAD+ injections)
−Headline microdosed tirzepatide price ($159/mo) requires a four-month plan billed upfront (~$636)
−Reviewers report slow support replies, billing/card-decline errors and heavy marketing email
Read the full AgelessRx review →

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address
+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500
+Third-party coverage reports named 503A pharmacy partners and free expedited shipping
−Compounded prices aren't visible on the public site; its product catalog failed to load during our research
−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published
−Site configuration shows an $80 initial visit fee that is not prominently disclosed
Read the full RxSpan MD review →

AgelessRx vs RxSpan MD — FAQ

Is AgelessRx better than RxSpan MD?

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AgelessRx scores higher overall in our independent evaluation (73.4/100 vs 59.1/100), leading on trust & safety, value, experience, product range, reputation.

Is AgelessRx or RxSpan MD cheaper?

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AgelessRx has the lower starting price (from $25/mo vs $30/mo for RxSpan MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do AgelessRx and RxSpan MD both offer?

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Both platforms treat Longevity & Peptides, Weight Loss / GLP-1. AgelessRx covers 4 treatment categories total and RxSpan MD covers 4.

Still deciding?