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AlphaMD vs Twentyeight Health: Which Is Better?

Head-to-head comparison of AlphaMD and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 64.6/100), leading on trust & safety, value, experience, product range, reputation.

65

AlphaMD is a small Washington-based TRT platform with published, commitment-tiered pricing from $98/mo, plus HCG, enclomiphene, female TRT, sermorelin, and NAD+.

Visit AlphaMD
75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionAlphaMDTwentyeight Health
Overall Score64.6/10075/100 ✓
Trust & Safety30%66/10076/100 ✓
Value25%72/10080/100 ✓
Experience20%60/10072/100 ✓
Product Range15%60/10072/100 ✓
Reputation10%58/10070/100 ✓

At a Glance

Founded—2018
HeadquartersLynnwood, WABrooklyn, NY
Publicly tradedNoNo
Treatment categories44
Treatments listed67
Starting price$50/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryAlphaMDTwentyeight Health
Women's Health$119
Female TRT
$15–$19.99
Complete Care Membership

AlphaMD

+Published TRT pricing with medication and supplies included: $98/mo annual, $109/mo semi-annual, $129/mo on a 3-month commitment
+20% discount for active military, veterans, and first responders
+Names its compounding pharmacy (AnazaoHealth, Tampa) and starts patients with a free at-home hormone test kit
−Every TRT plan carries a minimum commitment of at least 3 months
−Small review base (52 Trustpilot reviews), with complaints about unreturned calls and onboarding taking over a month
−Narrow catalog centered on testosterone; no weight-loss, hair-loss, or standalone ED program is published
Read the full AlphaMD review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

AlphaMD vs Twentyeight Health — FAQ

Is AlphaMD better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 64.6/100), leading on trust & safety, value, experience, product range, reputation.

Is AlphaMD or Twentyeight Health cheaper?

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Twentyeight Health has the lower starting price (from $15/mo vs $50/mo for AlphaMD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do AlphaMD and Twentyeight Health both offer?

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Both platforms treat Women's Health. AlphaMD covers 4 treatment categories total and Twentyeight Health covers 4.

Still deciding?

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