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Amble Health vs Defy Medical: Which Is Better?

Head-to-head comparison of Amble Health and Defy Medical based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 68.6/100), leading on trust & safety, experience, product range, reputation. Amble Health comes out ahead on value. Amble Health has the lower entry price (from $135/mo vs $150/mo), so the better value depends on which treatment you need.

Amble Health

Good

Amble Health is a 2023-founded compounded-GLP-1 telehealth brand offering flat, dose-independent monthly pricing for semaglutide and tirzepatide, bundled with consults and shipping.

Visit Amble Health

Defy Medical

Good

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical

Score Breakdown

Dimension	Amble Health	Defy Medical
Overall Score	68.6/100	71.9/100 ✓
Trust & Safety30%	68/100	72/100 ✓
Value25%	78/100 ✓	60/100
Experience20%	76/100	78/100 ✓
Product Range15%	50/100	78/100 ✓
Reputation10%	60/100	80/100 ✓

At a Glance

Founded	2023	2011
Headquarters	—	Tampa, FL
Publicly traded	No	No
Treatment categories	1	3
Treatments listed	2	4
Starting price	$135/mo	$150/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

Category	Amble Health	Defy Medical
Weight Loss / GLP-1	$135–$179 Compounded Semaglutide	$150–$250 GLP-1 Weight Loss (Semaglutide/Tirzepatide)

Amble Health

+Flat, all-in monthly pricing for compounded semaglutide and tirzepatide that doesn't change by dose, published on the website without an intake form

+Consult, medication, supplies, and shipping are all bundled into a single price with no add-on fees disclosed

+Longer-commitment discount structure rewards 6-12 month plans with the lowest per-month price ($135)

−Does not name its compounding pharmacy partner(s) publicly, unlike competitors that disclose 503A/503B sourcing

−Trustpilot complaints about medication arriving warm or thawed due to failed cold-chain packaging

−Multi-day delays reported for cancellation requests and billing dispute resolution

Read the full Amble Health review →

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)

+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours

+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing

−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront

−Some patients report delays of a week or more between consult and medication fulfillment

−Mobile app quality lags the web experience, per patient feedback

Read the full Defy Medical review →

Amble Health vs Defy Medical — FAQ

Is Amble Health better than Defy Medical?

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Is Amble Health or Defy Medical cheaper?

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Amble Health has the lower starting price (from $135/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Amble Health and Defy Medical both offer?

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Both platforms treat Weight Loss / GLP-1. Amble Health covers 1 treatment category total and Defy Medical covers 3.

Still deciding?

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