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Best Defy Medical Alternatives

Defy Medical scores 71.9/100 in our independent evaluation, but it isn't the right fit for everyone. The most common reasons people look elsewhere: pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront; and some patients report delays of a week or more between consult and medication fulfillment. Here are the 8 brands that compete with it most directly, ranked by category overlap and overall score.

Read our full Defy Medical review for the complete score breakdown.

#1
78
Very Good
Hone Health

Hone Health pairs an at-home 50+ biomarker blood panel with physician-directed hormone, weight-loss, and men's/women's health telehealth under a tiered membership model.

  • Higher overall score (77.5/100 vs 71.9/100)
  • Stronger trust & safety score (78 vs 72)
  • Better value score (70 vs 60)
#2
75
Good
Joi + Blokes

Combined men's and women's hormone-health telehealth brand offering TRT, BHRT, GLP-1 weight loss, peptide/longevity add-ons, and sexual-health treatment with no membership or consult fees.

  • Higher overall score (74.6/100 vs 71.9/100)
  • Better value score (78 vs 60)
  • Lower starting price ($59/mo vs $150/mo)
#3
72
Good
Rex MD

Rex MD is a men's-health telehealth brand — owned by publicly traded LifeMD — covering ED, premature ejaculation, TRT, hair loss, and GLP-1 treatment.

  • Higher overall score (72.2/100 vs 71.9/100)
  • Stronger trust & safety score (78 vs 72)
  • Lower starting price ($2/mo vs $150/mo)
#4
68
Good
LifeMD

Publicly traded telehealth betting big on weight loss, with aggressive GLP-1 pricing and fast-growing subscriber base.

  • Better value score (75 vs 60)
  • Lower starting price ($14/mo vs $150/mo)
  • Also treats Men's Health, Hair Loss, Dermatology
#5
66
Good
Rugiet

Men's telehealth platform best known for its compounded sublingual ED treatment combining sildenafil, tadalafil, and apomorphine in a single fast-acting dose.

  • Lower starting price ($49/mo vs $150/mo)
  • Also treats Men's Health, Hair Loss
#6
65
Good
Maximus

Maximus is a Santa Monica-based men's telehealth brand focused on testosterone and blood-flow (ED) protocols with published, comparison-ready pricing.

  • Better value score (68 vs 60)
  • Lower starting price ($49.99/mo vs $150/mo)
  • Also treats Men's Health
#7
64
Fair
Eden

DTC telehealth platform specializing in compounded GLP-1 weight-loss medications with flat-rate dose-independent pricing and the world's first compounded GLP-1 gummy.

  • Better value score (70 vs 60)
  • Lower starting price ($124/mo vs $150/mo)
  • Also treats Men's Health, Hair Loss, Dermatology
#8
62
Fair
Male Excel

TRT-focused telehealth clinic specializing in daily microdosing testosterone protocols with bundled monitoring, serving 100,000+ men since 2018.

  • Lower starting price ($65/mo vs $150/mo)
  • Also treats Men's Health

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