HomeCompareDefy Medical vs Hone Health

Defy Medical vs Hone Health: Which Is Better?

Head-to-head comparison of Defy Medical and Hone Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Hone Health scores higher overall in our independent evaluation (77.5/100 vs 71.9/100), leading on trust & safety, value, experience, product range. Defy Medical comes out ahead on reputation.

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

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78
Hone Health
Very Good

Hone Health pairs an at-home 50+ biomarker blood panel with physician-directed hormone, weight-loss, and men's/women's health telehealth under a tiered membership model.

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Score Breakdown

DimensionDefy MedicalHone Health
Overall Score71.9/10077.5/100
Trust & Safety30%72/10078/100
Value25%60/10070/100
Experience20%78/10080/100
Product Range15%78/10085/100
Reputation10%80/10078/100

At a Glance

Founded20112020
HeadquartersTampa, FLNew York, NY
Publicly tradedNoNo
Treatment categories35
Treatments listed46
Starting price$150/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalHone Health
Hormone Therapy$150–$250
Women's Bioidentical HRT
$25–$155
TRT Program (injections/cream/enclomiphene)
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$155–$350
GLP-1 Weight Loss
Sexual Health$25–$155
ED Medication

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
Some patients report delays of a week or more between consult and medication fulfillment
Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Hone Health

+Biomarker testing (50+ markers) grounds treatment decisions in lab data rather than a simple intake questionnaire
+Broad category range spanning hormone therapy, weight loss, sexual health, and hair loss under one platform
+Large volume of positive patient feedback (4.8/5 across 12,359 Trustpilot reviews), concentrated on physician quality
Premium membership tier ($155/mo) required to unlock some treatments, which reviewers report wasn't made clear at signup
Support responsiveness complaints, including same-day appointment cancellations
Full treatment pricing isn't visible until after the $65 paid assessment
Read the full Hone Health review →

Defy Medical vs Hone Health — FAQ

Is Defy Medical better than Hone Health?

Hone Health scores higher overall in our independent evaluation (77.5/100 vs 71.9/100), leading on trust & safety, value, experience, product range. Defy Medical comes out ahead on reputation.

Is Defy Medical or Hone Health cheaper?

Hone Health has the lower starting price (from $25/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and Hone Health both offer?

Both platforms treat Hormone Therapy, Weight Loss / GLP-1, Sexual Health. Defy Medical covers 3 treatment categories total and Hone Health covers 5.

Still deciding?