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Amble Health vs Twentyeight Health: Which Is Better?

Head-to-head comparison of Amble Health and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 68.6/100), leading on trust & safety, value, product range, reputation. Amble Health comes out ahead on experience.

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Amble Health is a 2023-founded compounded-GLP-1 telehealth brand offering flat, dose-independent monthly pricing for semaglutide and tirzepatide, bundled with consults and shipping.

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Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionAmble HealthTwentyeight Health
Overall Score68.6/10075/100 ✓
Trust & Safety30%68/10076/100 ✓
Value25%78/10080/100 ✓
Experience20%76/100 ✓72/100
Product Range15%50/10072/100 ✓
Reputation10%60/10070/100 ✓

At a Glance

Founded20232018
Headquarters—Brooklyn, NY
Publicly tradedNoNo
Treatment categories14
Treatments listed27
Starting price$135/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryAmble HealthTwentyeight Health
Weight Loss / GLP-1$135–$179
Compounded Semaglutide
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Amble Health

+Flat, all-in monthly pricing for compounded semaglutide and tirzepatide that doesn't change by dose, published on the website without an intake form
+Consult, medication, supplies, and shipping are all bundled into a single price with no add-on fees disclosed
+Longer-commitment discount structure rewards 6-12 month plans with the lowest per-month price ($135)
−Does not name its compounding pharmacy partner(s) publicly, unlike competitors that disclose 503A/503B sourcing
−Trustpilot complaints about medication arriving warm or thawed due to failed cold-chain packaging
−Multi-day delays reported for cancellation requests and billing dispute resolution
Read the full Amble Health review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

Amble Health vs Twentyeight Health — FAQ

Is Amble Health better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 68.6/100), leading on trust & safety, value, product range, reputation. Amble Health comes out ahead on experience.

Is Amble Health or Twentyeight Health cheaper?

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Twentyeight Health has the lower starting price (from $15/mo vs $135/mo for Amble Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Amble Health and Twentyeight Health both offer?

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Both platforms treat Weight Loss / GLP-1. Amble Health covers 1 treatment category total and Twentyeight Health covers 4.

Still deciding?

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