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Brightmeds vs ProlongMD: Which Is Better?

Head-to-head comparison of Brightmeds and ProlongMD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Brightmeds scores higher overall in our independent evaluation (66.5/100 vs 60.1/100), leading on trust & safety, experience, product range, reputation. ProlongMD comes out ahead on value. ProlongMD has the lower entry price (from $25/mo vs $99/mo), so the better value depends on which treatment you need.

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Brightmeds is a Florida-based telehealth storefront selling flat-priced compounded GLP-1s alongside TRT, sermorelin, NAD+ and glutathione, with care from third-party medical groups.

Visit Brightmeds
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Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD

Score Breakdown

DimensionBrightmedsProlongMD
Overall Score66.5/100 ✓60.1/100
Trust & Safety30%60/100 ✓52/100
Value25%70/10074/100 ✓
Experience20%72/100 ✓55/100
Product Range15%72/100 ✓70/100
Reputation10%58/100 ✓45/100

At a Glance

Founded20232025
HeadquartersBrandon, FLPhoenix, AZ
Publicly tradedNoNo
Treatment categories48
Treatments listed713
Starting price$99/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryBrightmedsProlongMD
Weight Loss / GLP-1$99–$399
Compounded Semaglutide
$99–$119
Compounded Semaglutide/B12
Hormone Therapy$299–$325
Testosterone Replacement Therapy
$89–$119
Testosterone Cypionate (200 mg/mL)
Men's Health—$129–$159
Enclomiphene 25 mg
Longevity & Peptides$99–$199
Glutathione
$179
Sermorelin

Brightmeds

+Terms name its prescribing medical groups (M & D Integrations, TelegraMD) and dispensing pharmacies (Southend, Red Rock)
+Flat GLP-1 pricing at every dose, with visits and shipping bundled and a refund if not approved
+TRT program includes lab testing for the first year plus quarterly check-ins
−Prices for the same drug differ by landing page (semaglutide $129/mo on promo pages vs $289–399/mo elsewhere)
−Longevity and TRT prices are not shown on the main product catalog and are only visible inside individual funnels
−Short operating history; LLC formed December 2023
Read the full Brightmeds review →

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

Brightmeds vs ProlongMD — FAQ

Is Brightmeds better than ProlongMD?

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Brightmeds scores higher overall in our independent evaluation (66.5/100 vs 60.1/100), leading on trust & safety, experience, product range, reputation. ProlongMD comes out ahead on value. ProlongMD has the lower entry price (from $25/mo vs $99/mo), so the better value depends on which treatment you need.

Is Brightmeds or ProlongMD cheaper?

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ProlongMD has the lower starting price (from $25/mo vs $99/mo for Brightmeds). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Brightmeds and ProlongMD both offer?

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Both platforms treat Weight Loss / GLP-1, Hormone Therapy, Men's Health, Longevity & Peptides. Brightmeds covers 4 treatment categories total and ProlongMD covers 8.

Still deciding?

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