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Brightmeds vs Twentyeight Health: Which Is Better?

Head-to-head comparison of Brightmeds and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 66.5/100), leading on trust & safety, value, reputation.

67

Brightmeds is a Florida-based telehealth storefront selling flat-priced compounded GLP-1s alongside TRT, sermorelin, NAD+ and glutathione, with care from third-party medical groups.

Visit Brightmeds
75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionBrightmedsTwentyeight Health
Overall Score66.5/10075/100 ✓
Trust & Safety30%60/10076/100 ✓
Value25%70/10080/100 ✓
Experience20%72/10072/100
Product Range15%72/10072/100
Reputation10%58/10070/100 ✓

At a Glance

Founded20232018
HeadquartersBrandon, FLBrooklyn, NY
Publicly tradedNoNo
Treatment categories44
Treatments listed77
Starting price$99/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryBrightmedsTwentyeight Health
Weight Loss / GLP-1$99–$399
Compounded Semaglutide
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Brightmeds

+Terms name its prescribing medical groups (M & D Integrations, TelegraMD) and dispensing pharmacies (Southend, Red Rock)
+Flat GLP-1 pricing at every dose, with visits and shipping bundled and a refund if not approved
+TRT program includes lab testing for the first year plus quarterly check-ins
−Prices for the same drug differ by landing page (semaglutide $129/mo on promo pages vs $289–399/mo elsewhere)
−Longevity and TRT prices are not shown on the main product catalog and are only visible inside individual funnels
−Short operating history; LLC formed December 2023
Read the full Brightmeds review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

Brightmeds vs Twentyeight Health — FAQ

Is Brightmeds better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 66.5/100), leading on trust & safety, value, reputation.

Is Brightmeds or Twentyeight Health cheaper?

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Twentyeight Health has the lower starting price (from $15/mo vs $99/mo for Brightmeds). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Brightmeds and Twentyeight Health both offer?

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Both platforms treat Weight Loss / GLP-1. Brightmeds covers 4 treatment categories total and Twentyeight Health covers 4.

Still deciding?

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