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Calibrate vs He & She MD: Which Is Better?

Head-to-head comparison of Calibrate and He & She MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Calibrate scores higher overall in our independent evaluation (66.9/100 vs 65.3/100), leading on trust & safety, experience, reputation. He & She MD comes out ahead on value, product range.

67

Calibrate is a year-long metabolic-reset program pairing coaching and biomarker tracking with insurance-navigated branded GLP-1 prescribing — built for members who already have GLP-1 coverage, not cash-pay patients.

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65

He & She MD is a Newport Beach-based men's and women's telehealth brand covering GLP-1s, longevity injectables, HRT, testosterone, hair loss and ED, with the lowest prices tied to long prepaid terms.

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Score Breakdown

DimensionCalibrateHe & She MD
Overall Score66.9/100 ✓65.3/100
Trust & Safety30%76/100 ✓58/100
Value25%58/10074/100 ✓
Experience20%72/100 ✓60/100
Product Range15%60/10084/100 ✓
Reputation10%62/100 ✓48/100

At a Glance

Founded20192025
HeadquartersNew York, NYNewport Beach, CA
Publicly tradedNoNo
Treatment categories17
Treatments listed213
Starting price$25/mo$60/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryCalibrateHe & She MD
Weight Loss / GLP-1$25–$1350
Insurance-Navigated Branded GLP-1
$99–$199
Compounded Semaglutide (injectable)

Calibrate

+Comprehensive year-long program combining 1:1 coaching, biomarker/lab review, and a connected smart scale alongside GLP-1 prescribing
+Insurance-navigation support aims to get members GLP-1 medication near a $25/month copay when commercial coverage applies
+Strong Trustpilot rating (4.5/5, ~1,200 reviews) with many members reporting 40-70+ lb losses
−Poor fit and high cost for cash-pay patients without GLP-1 insurance coverage — medication bills separately and can approach full brand retail (roughly $1,000+/month) if a plan doesn't cover it
−$199/month program fee requires a 3-month minimum commitment ($597) before month-to-month conversion
−Reports of 3+ week waits for medication-dose changes and inconsistent coach assignment session-to-session
Read the full Calibrate review →

He & She MD

+Broad catalog covering compounded GLP-1s (injectable and oral), NAD+, sermorelin, glutathione, estradiol/progesterone HRT, testosterone, enclomiphene, hair loss and ED
+Names its dispensing pharmacies and the states where one partner cannot ship sterile compounds
+Low entry pricing on long terms: compounded semaglutide $99/mo on annual prepay, hair loss $79/mo, ED from $10/dose
−Site shows '4.8 Excellent' and 5.0 rating badges while its Trustpilot profile has zero reviews, so the ratings can't be verified
−Most headline prices require 3- to 12-month prepayment; month-to-month semaglutide is $199 and tirzepatide $299
−Platform terms allow a $15 fee per additional consult or lab-result interpretation on top of plan prices
Read the full He & She MD review →

Calibrate vs He & She MD — FAQ

Is Calibrate better than He & She MD?

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Calibrate scores higher overall in our independent evaluation (66.9/100 vs 65.3/100), leading on trust & safety, experience, reputation. He & She MD comes out ahead on value, product range.

Is Calibrate or He & She MD cheaper?

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Calibrate has the lower starting price (from $25/mo vs $60/mo for He & She MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Calibrate and He & She MD both offer?

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Both platforms treat Weight Loss / GLP-1. Calibrate covers 1 treatment category total and He & She MD covers 7.

Still deciding?

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