Home›Compare›Calibrate vs ProlongMD

Calibrate vs ProlongMD: Which Is Better?

Head-to-head comparison of Calibrate and ProlongMD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Calibrate scores higher overall in our independent evaluation (66.9/100 vs 60.1/100), leading on trust & safety, experience, reputation. ProlongMD comes out ahead on value, product range.

67

Calibrate is a year-long metabolic-reset program pairing coaching and biomarker tracking with insurance-navigated branded GLP-1 prescribing — built for members who already have GLP-1 coverage, not cash-pay patients.

Visit Calibrate
60

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD

Score Breakdown

DimensionCalibrateProlongMD
Overall Score66.9/100 ✓60.1/100
Trust & Safety30%76/100 ✓52/100
Value25%58/10074/100 ✓
Experience20%72/100 ✓55/100
Product Range15%60/10070/100 ✓
Reputation10%62/100 ✓45/100

At a Glance

Founded20192025
HeadquartersNew York, NYPhoenix, AZ
Publicly tradedNoNo
Treatment categories18
Treatments listed213
Starting price$25/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryCalibrateProlongMD
Weight Loss / GLP-1$25–$1350
Insurance-Navigated Branded GLP-1
$99–$119
Compounded Semaglutide/B12

Calibrate

+Comprehensive year-long program combining 1:1 coaching, biomarker/lab review, and a connected smart scale alongside GLP-1 prescribing
+Insurance-navigation support aims to get members GLP-1 medication near a $25/month copay when commercial coverage applies
+Strong Trustpilot rating (4.5/5, ~1,200 reviews) with many members reporting 40-70+ lb losses
−Poor fit and high cost for cash-pay patients without GLP-1 insurance coverage — medication bills separately and can approach full brand retail (roughly $1,000+/month) if a plan doesn't cover it
−$199/month program fee requires a 3-month minimum commitment ($597) before month-to-month conversion
−Reports of 3+ week waits for medication-dose changes and inconsistent coach assignment session-to-session
Read the full Calibrate review →

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

Calibrate vs ProlongMD — FAQ

Is Calibrate better than ProlongMD?

▾

Calibrate scores higher overall in our independent evaluation (66.9/100 vs 60.1/100), leading on trust & safety, experience, reputation. ProlongMD comes out ahead on value, product range.

Is Calibrate or ProlongMD cheaper?

▾

Their entry prices are similar — both start around $25/mo. Real cost depends on the specific treatment: compare the pricing tables on each review, since inclusions like consults, labs, and shipping differ.

What do Calibrate and ProlongMD both offer?

▾

Both platforms treat Weight Loss / GLP-1. Calibrate covers 1 treatment category total and ProlongMD covers 8.

Still deciding?

Calibrate alternativesProlongMD alternativesTake the Match Quiz