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Calibrate vs RxSpan MD: Which Is Better?

Head-to-head comparison of Calibrate and RxSpan MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Calibrate scores higher overall in our independent evaluation (66.9/100 vs 59.1/100), leading on trust & safety, experience, reputation. RxSpan MD comes out ahead on product range.

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Calibrate is a year-long metabolic-reset program pairing coaching and biomarker tracking with insurance-navigated branded GLP-1 prescribing — built for members who already have GLP-1 coverage, not cash-pay patients.

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RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

Visit RxSpan MD

Score Breakdown

DimensionCalibrateRxSpan MD
Overall Score66.9/100 ✓59.1/100
Trust & Safety30%76/100 ✓60/100
Value25%58/10058/100
Experience20%72/100 ✓52/100
Product Range15%60/10078/100 ✓
Reputation10%62/100 ✓45/100

At a Glance

Founded20192026
HeadquartersNew York, NYBeverly Hills, CA
Publicly tradedNoNo
Treatment categories14
Treatments listed29
Starting price$25/mo$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryCalibrateRxSpan MD
Weight Loss / GLP-1$25–$1350
Insurance-Navigated Branded GLP-1
$249–$299
Compounded Semaglutide (injection or oral)

Calibrate

+Comprehensive year-long program combining 1:1 coaching, biomarker/lab review, and a connected smart scale alongside GLP-1 prescribing
+Insurance-navigation support aims to get members GLP-1 medication near a $25/month copay when commercial coverage applies
+Strong Trustpilot rating (4.5/5, ~1,200 reviews) with many members reporting 40-70+ lb losses
−Poor fit and high cost for cash-pay patients without GLP-1 insurance coverage — medication bills separately and can approach full brand retail (roughly $1,000+/month) if a plan doesn't cover it
−$199/month program fee requires a 3-month minimum commitment ($597) before month-to-month conversion
−Reports of 3+ week waits for medication-dose changes and inconsistent coach assignment session-to-session
Read the full Calibrate review →

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address
+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500
+Third-party coverage reports named 503A pharmacy partners and free expedited shipping
−Compounded prices aren't visible on the public site; its product catalog failed to load during our research
−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published
−Site configuration shows an $80 initial visit fee that is not prominently disclosed
Read the full RxSpan MD review →

Calibrate vs RxSpan MD — FAQ

Is Calibrate better than RxSpan MD?

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Calibrate scores higher overall in our independent evaluation (66.9/100 vs 59.1/100), leading on trust & safety, experience, reputation. RxSpan MD comes out ahead on product range.

Is Calibrate or RxSpan MD cheaper?

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Calibrate has the lower starting price (from $25/mo vs $30/mo for RxSpan MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Calibrate and RxSpan MD both offer?

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Both platforms treat Weight Loss / GLP-1. Calibrate covers 1 treatment category total and RxSpan MD covers 4.

Still deciding?