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Calibrate vs Yucca Health: Which Is Better?

Head-to-head comparison of Calibrate and Yucca Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Yucca Health scores higher overall in our independent evaluation (68.3/100 vs 66.9/100), leading on value. Calibrate comes out ahead on trust & safety, product range, reputation. Calibrate has the lower entry price (from $25/mo vs $125/mo), so the better value depends on which treatment you need.

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Calibrate is a year-long metabolic-reset program pairing coaching and biomarker tracking with insurance-navigated branded GLP-1 prescribing — built for members who already have GLP-1 coverage, not cash-pay patients.

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68

Yucca Health is a Beverly Hills-based telehealth platform selling compounded semaglutide and tirzepatide at flat, dose-independent prices, plus compounded NAD+ and sermorelin.

Visit Yucca Health

Score Breakdown

DimensionCalibrateYucca Health
Overall Score66.9/10068.3/100 ✓
Trust & Safety30%76/100 ✓64/100
Value25%58/10080/100 ✓
Experience20%72/10072/100
Product Range15%60/100 ✓58/100
Reputation10%62/100 ✓60/100

At a Glance

Founded20192025
HeadquartersNew York, NYBeverly Hills, CA
Publicly tradedNoNo
Treatment categories12
Treatments listed24
Starting price$25/mo$125/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryCalibrateYucca Health
Weight Loss / GLP-1$25–$1350
Insurance-Navigated Branded GLP-1
$125–$146
Compounded Semaglutide+ (injectable)

Calibrate

+Comprehensive year-long program combining 1:1 coaching, biomarker/lab review, and a connected smart scale alongside GLP-1 prescribing
+Insurance-navigation support aims to get members GLP-1 medication near a $25/month copay when commercial coverage applies
+Strong Trustpilot rating (4.5/5, ~1,200 reviews) with many members reporting 40-70+ lb losses
−Poor fit and high cost for cash-pay patients without GLP-1 insurance coverage — medication bills separately and can approach full brand retail (roughly $1,000+/month) if a plan doesn't cover it
−$199/month program fee requires a 3-month minimum commitment ($597) before month-to-month conversion
−Reports of 3+ week waits for medication-dose changes and inconsistent coach assignment session-to-session
Read the full Calibrate review →

Yucca Health

+Full price grid published before intake: semaglutide $146/mo monthly, $140/mo quarterly or $125/mo on a 6-month prepay; tirzepatide $258, $248 or $225/mo
+Locked pricing covers the whole dose range, so titrating up does not raise the bill; pausing keeps the locked rate
+No separate membership or consultation fee; plans include the provider consult, medication, injection supplies and free 2-day shipping
−Dispensing pharmacies are not named on the public site; they appear only in the patient portal and on the label after ordering
−BBB rating of C+ (not accredited) with five closed complaints; one Trustpilot reviewer reports prepaying six months and receiving three
−About 6% of roughly 1,230 Trustpilot reviews are 1-star, citing lack of results after months of treatment and refund disputes
Read the full Yucca Health review →

Calibrate vs Yucca Health — FAQ

Is Calibrate better than Yucca Health?

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Yucca Health scores higher overall in our independent evaluation (68.3/100 vs 66.9/100), leading on value. Calibrate comes out ahead on trust & safety, product range, reputation. Calibrate has the lower entry price (from $25/mo vs $125/mo), so the better value depends on which treatment you need.

Is Calibrate or Yucca Health cheaper?

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Calibrate has the lower starting price (from $25/mo vs $125/mo for Yucca Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Calibrate and Yucca Health both offer?

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Both platforms treat Weight Loss / GLP-1. Calibrate covers 1 treatment category total and Yucca Health covers 2.

Still deciding?

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