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Defy Medical vs Evolve Telemedicine: Which Is Better?

Head-to-head comparison of Defy Medical and Evolve Telemedicine based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 55.3/100), leading on trust & safety, value, experience, product range, reputation. Evolve Telemedicine has the lower entry price (from $149.99/mo vs $150/mo), so the better value depends on which treatment you need.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
55

A small concierge-style telehealth operator selling compounded hormone, weight-loss, and wellness therapies through a paid membership.

Visit Evolve Telemedicine

Score Breakdown

DimensionDefy MedicalEvolve Telemedicine
Overall Score71.9/100 ✓55.3/100
Trust & Safety30%72/100 ✓55/100
Value25%60/100 ✓48/100
Experience20%78/100 ✓60/100
Product Range15%78/100 ✓65/100
Reputation10%80/100 ✓50/100

At a Glance

Founded2011—
HeadquartersTampa, FLBloomfield Hills, MI
Publicly tradedNoNo
Treatment categories33
Treatments listed45
Starting price$150/mo$149.99/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalEvolve Telemedicine
Hormone Therapy$150–$250
Women's Bioidentical HRT
$149.99
Baseline Labs
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$400–$600
Compounded Semaglutide
Sexual Health——

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Evolve Telemedicine

+Broad concierge-style hormone and wellness menu (BHRT, TRT, thyroid support, peptide therapy, GLP-1 weight loss, sexual wellness, hair) under one membership with a free initial consult.
+Reports (per prior research, not independently verified on-site) shipping compounded medications to patients in all 50 states.
+A majority of Trustpilot reviewers (78% five-star) describe knowledgeable, thorough clinical staff.
−Reviewers report medication price increases of 200-300% within a few months of enrolling, with claims that comparable prescriptions cost significantly less elsewhere.
−Trustpilot sample is small (54 reviews) — too limited to draw strong reputational conclusions despite the 4.1 average.
−Lab result and refill turnaround delays are a recurring complaint, with patients told to request refills 20-25 days in advance to avoid running out.
Read the full Evolve Telemedicine review →

Defy Medical vs Evolve Telemedicine — FAQ

Is Defy Medical better than Evolve Telemedicine?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 55.3/100), leading on trust & safety, value, experience, product range, reputation. Evolve Telemedicine has the lower entry price (from $149.99/mo vs $150/mo), so the better value depends on which treatment you need.

Is Defy Medical or Evolve Telemedicine cheaper?

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Evolve Telemedicine has the lower starting price (from $149.99/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and Evolve Telemedicine both offer?

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Both platforms treat Hormone Therapy, Weight Loss / GLP-1, Sexual Health. Defy Medical covers 3 treatment categories total and Evolve Telemedicine covers 3.

Still deciding?

Defy Medical alternativesEvolve Telemedicine alternativesTake the Match Quiz