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Defy Medical vs Fridays: Which Is Better?

Head-to-head comparison of Defy Medical and Fridays based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 55.3/100), leading on trust & safety, experience, product range, reputation. Fridays comes out ahead on value. Fridays has the lower entry price (from $98/mo vs $150/mo), so the better value depends on which treatment you need.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
55

Bootstrapped GLP-1 weight-management clinic offering compounded semaglutide and tirzepatide with bundled dietitian, fitness, and mental health coaching.

Visit Fridays

Score Breakdown

DimensionDefy MedicalFridays
Overall Score71.9/100 ✓55.3/100
Trust & Safety30%72/100 ✓55/100
Value25%60/10075/100 ✓
Experience20%78/100 ✓50/100
Product Range15%78/100 ✓30/100
Reputation10%80/100 ✓55/100

At a Glance

Founded20112023
HeadquartersTampa, FLIrvine, CA
Publicly tradedNoNo
Treatment categories31
Treatments listed45
Starting price$150/mo$98/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalFridays
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$98
Branded Wegovy (Pill or Pen)

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Fridays

+Comprehensive all-inclusive pricing: labs, unlimited visits, dietitian, mental health support, and fitness app bundled
+Competitive compounded GLP-1 pricing starting at $150/mo on annual plan
+Unique insurance concierge handles prior authorizations for brand-name GLP-1s
−BBB 'F' rating — failed to respond to 9 out of 11 complaints
−Reports of ineffective compounded semaglutide; one customer received medication from pharmacy with health violations
−Billing problems: duplicate charges (one customer charged 6 times), difficulty canceling
Read the full Fridays review →

Defy Medical vs Fridays — FAQ

Is Defy Medical better than Fridays?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 55.3/100), leading on trust & safety, experience, product range, reputation. Fridays comes out ahead on value. Fridays has the lower entry price (from $98/mo vs $150/mo), so the better value depends on which treatment you need.

Is Defy Medical or Fridays cheaper?

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Fridays has the lower starting price (from $98/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and Fridays both offer?

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Both platforms treat Weight Loss / GLP-1. Defy Medical covers 3 treatment categories total and Fridays covers 1.

Still deciding?

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