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Defy Medical vs Henry Meds: Which Is Better?

Head-to-head comparison of Defy Medical and Henry Meds based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 68.8/100), leading on trust & safety, experience, product range, reputation. Henry Meds comes out ahead on value. Henry Meds has the lower entry price (from $50/mo vs $150/mo), so the better value depends on which treatment you need.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
69

One of the largest GLP-1 telehealth brands by review volume, offering flat all-inclusive monthly pricing with meaningful prepay discounts.

Visit Henry Meds

Score Breakdown

DimensionDefy MedicalHenry Meds
Overall Score71.9/100 ✓68.8/100
Trust & Safety30%72/100 ✓68/100
Value25%60/10070/100 ✓
Experience20%78/100 ✓75/100
Product Range15%78/100 ✓58/100
Reputation10%80/100 ✓72/100

At a Glance

Founded2011—
HeadquartersTampa, FL—
Publicly tradedNoNo
Treatment categories31
Treatments listed44
Starting price$150/mo$50/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalHenry Meds
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$50–$90
Phentermine

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Henry Meds

+One of the largest GLP-1 telehealth brands by review volume (12,527 Trustpilot reviews, 4.4 average)
+Flat, all-inclusive monthly pricing bundles visit, medication, and supplies
+Meaningful prepay discount structure ($297 to $197/mo) rewards longer commitments
−Customer support frequently described as hard to reach by phone, with 7-10 day email response times reported
−Some patients report scheduled provider appointments with no-shows
−California residents face longer shipping times due to added compound-testing requirements
Read the full Henry Meds review →

Defy Medical vs Henry Meds — FAQ

Is Defy Medical better than Henry Meds?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 68.8/100), leading on trust & safety, experience, product range, reputation. Henry Meds comes out ahead on value. Henry Meds has the lower entry price (from $50/mo vs $150/mo), so the better value depends on which treatment you need.

Is Defy Medical or Henry Meds cheaper?

▾

Henry Meds has the lower starting price (from $50/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and Henry Meds both offer?

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Both platforms treat Weight Loss / GLP-1. Defy Medical covers 3 treatment categories total and Henry Meds covers 1.

Still deciding?

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