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Defy Medical vs OrderlyMeds: Which Is Better?

Head-to-head comparison of Defy Medical and OrderlyMeds based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 54.8/100), leading on trust & safety, value, experience, product range, reputation. OrderlyMeds has the lower entry price (from $74/mo vs $150/mo), so the better value depends on which treatment you need.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
55
OrderlyMeds
Below Average

2024-founded compounded GLP-1 telehealth service with low entry pricing and add-on wellness perks, but a below-average Trustpilot track record.

Visit OrderlyMeds

Score Breakdown

DimensionDefy MedicalOrderlyMeds
Overall Score71.9/100 ✓54.8/100
Trust & Safety30%72/100 ✓55/100
Value25%60/100 ✓58/100
Experience20%78/100 ✓50/100
Product Range15%78/100 ✓62/100
Reputation10%80/100 ✓45/100

At a Glance

Founded20112024
HeadquartersTampa, FL—
Publicly tradedNoNo
Treatment categories31
Treatments listed44
Starting price$150/mo$74/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalOrderlyMeds
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$74–$149
Compounded Semaglutide

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

OrderlyMeds

+Transparent about which named 503A pharmacies fulfill prescriptions
+Low advertised starter pricing ($74-149/mo) provides an accessible entry point
+Bundled extras (BetterHelp therapy access, Trifecta fitness app, nutrition guides) add value beyond medication
−Starter pricing roughly doubles after the first cycle ($74 to $149, $149 to $299/mo), which can surprise patients
−Trustpilot rating of only 3.6/5 with reports of shipping delays and heat-damaged packages
−A licensed pharmacist has publicly flagged concerns about the company's beyond-use-date prescribing practices
Read the full OrderlyMeds review →

Defy Medical vs OrderlyMeds — FAQ

Is Defy Medical better than OrderlyMeds?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 54.8/100), leading on trust & safety, value, experience, product range, reputation. OrderlyMeds has the lower entry price (from $74/mo vs $150/mo), so the better value depends on which treatment you need.

Is Defy Medical or OrderlyMeds cheaper?

▾

OrderlyMeds has the lower starting price (from $74/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and OrderlyMeds both offer?

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Both platforms treat Weight Loss / GLP-1. Defy Medical covers 3 treatment categories total and OrderlyMeds covers 1.

Still deciding?

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