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Defy Medical vs Ro: Which Is Better?

Head-to-head comparison of Defy Medical and Ro based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Ro scores higher overall in our independent evaluation (77/100 vs 71.9/100), leading on trust & safety, value, experience. Defy Medical comes out ahead on product range.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
77
Ro
Very Good

Vertically integrated private telehealth with in-house pharmacy, diagnostics, and an Eli Lilly partnership for branded GLP-1s.

Visit Ro

Score Breakdown

DimensionDefy MedicalRo
Overall Score71.9/10077/100 ✓
Trust & Safety30%72/10085/100 ✓
Value25%60/10065/100 ✓
Experience20%78/10080/100 ✓
Product Range15%78/100 ✓75/100
Reputation10%80/10080/100

At a Glance

Founded20112017
HeadquartersTampa, FLNew York, NY
Publicly tradedNoNo
Treatment categories35
Treatments listed49
Starting price$150/mo$13/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalRo
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$149–$299
Branded Wegovy Pill (oral semaglutide)
Sexual Health—$32–$80
Sildenafil

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Ro

+Direct Eli Lilly partnership for branded Zepbound
+Novo Nordisk partnership for branded Wegovy pill at lowest cash-pay price
+In-house pharmacy and diagnostics lab
−Higher prices than competitors using compounded medications
−$145/mo membership fee on top of medication costs
−Narrower treatment range than Hims & Hers
Read the full Ro review →

Defy Medical vs Ro — FAQ

Is Defy Medical better than Ro?

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Ro scores higher overall in our independent evaluation (77/100 vs 71.9/100), leading on trust & safety, value, experience. Defy Medical comes out ahead on product range.

Is Defy Medical or Ro cheaper?

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Ro has the lower starting price (from $13/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and Ro both offer?

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Both platforms treat Weight Loss / GLP-1, Sexual Health. Defy Medical covers 3 treatment categories total and Ro covers 5.

Still deciding?

Defy Medical alternativesRo alternativesTake the Match Quiz