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Defy Medical vs Willow: Which Is Better?

Head-to-head comparison of Defy Medical and Willow based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
52
Willow
Below Average

Women-focused compounded GLP-1 telehealth brand operating in a limited number of states, tied to a National Advertising Division referral over its marketing claims.

Visit Willow

Score Breakdown

DimensionDefy MedicalWillow
Overall Score71.9/100 ✓51.9/100
Trust & Safety30%72/100 ✓48/100
Value25%60/100 ✓52/100
Experience20%78/100 ✓62/100
Product Range15%78/100 ✓55/100
Reputation10%80/100 ✓38/100

At a Glance

Founded2011—
HeadquartersTampa, FL—
Publicly tradedNoNo
Treatment categories32
Treatments listed42
Starting price$150/mo$299/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalWillow
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
$299
Compounded Semaglutide

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Willow

+Women-focused positioning with unlimited doctor access included in plan price
+Reviewers highlight responsive, board-certified doctors and simple onboarding
+Some patients report substantial results (e.g., 65 lbs in three months)
−Reportedly referred by the National Advertising Division to state attorneys general (Dec 2025) over advertising claims — unverified independently this cycle, needs manual confirmation
−Service limited to a narrow footprint (reportedly ~12 states), well below most national competitors
−Pricing ($299-399/mo starting) runs higher than several direct compounded-GLP-1 competitors
Read the full Willow review →

Defy Medical vs Willow — FAQ

Is Defy Medical better than Willow?

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Defy Medical scores higher overall in our independent evaluation (71.9/100 vs 51.9/100), leading on trust & safety, value, experience, product range, reputation.

Is Defy Medical or Willow cheaper?

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Defy Medical has the lower starting price (from $150/mo vs $299/mo for Willow). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and Willow both offer?

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Both platforms treat Weight Loss / GLP-1. Defy Medical covers 3 treatment categories total and Willow covers 2.

Still deciding?

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