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Defy Medical vs Wisp: Which Is Better?

Head-to-head comparison of Defy Medical and Wisp based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Wisp scores higher overall in our independent evaluation (73.6/100 vs 71.9/100), leading on value. Defy Medical comes out ahead on experience, product range, reputation.

72

Physician-led telemedicine hormone clinic offering TRT, women's HRT, peptides, GLP-1s, and sexual-health treatments through its own 503B pharmacy.

Visit Defy Medical
74
Wisp
Good

Async telehealth platform for sexual and reproductive health, prescribing UTI, BV, yeast, herpes, STI, birth control, and menopause treatment at scale with no consult fee.

Visit Wisp

Score Breakdown

DimensionDefy MedicalWisp
Overall Score71.9/10073.6/100 ✓
Trust & Safety30%72/10072/100
Value25%60/10078/100 ✓
Experience20%78/100 ✓70/100
Product Range15%78/100 ✓75/100
Reputation10%80/100 ✓72/100

At a Glance

Founded20112018
HeadquartersTampa, FLAustin, TX
Publicly tradedNoNo
Treatment categories34
Treatments listed44
Starting price$150/mo$5/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDefy MedicalWisp
Weight Loss / GLP-1$150–$250
GLP-1 Weight Loss (Semaglutide/Tirzepatide)
—
Sexual Health—$40–$70
Herpes / Cold Sore Antiviral Treatment

Defy Medical

+15 years in operation (founded 2011) — one of the longest-running cash-pay hormone-therapy telehealth brands, with a named Medical Director (Dr. Justin Saya)
+Trustpilot rating of 4.8/5 across 4,144 reviews, and the company responds to 94% of negative reviews, typically within 24 hours
+Broad treatment range from a single provider — TRT, women's HRT, peptides, GLP-1s, sexual dysfunction, and hair loss — dispensed through its own 503B-registered pharmacy with labs required before prescribing
−Pricing is not published on the website; patients must complete a roughly $250 consult before learning treatment costs, a transparency gap versus competitors that post pricing upfront
−Some patients report delays of a week or more between consult and medication fulfillment
−Mobile app quality lags the web experience, per patient feedback
Read the full Defy Medical review →

Wisp

+No consult fee, with async intake and prescriptions typically issued within hours
+Broad service line under one account: UTI, BV, yeast, herpes, STI treatment/prevention (including DoxyPEP), birth control, and menopause care
+Large scale and review base (2M+ patients, 11,496 Trustpilot reviews at 4.1) indicating consistent service delivery
−Recurring reports of patients being charged for prescriptions that were never sent to the pharmacy, paired with difficulty reaching phone support
−Some patients report side effects or mismatched treatment, suggesting async intake screening can miss individual nuance a live visit would catch
−Weight-care and membership pricing are not fully published prior to starting an intake
Read the full Wisp review →

Defy Medical vs Wisp — FAQ

Is Defy Medical better than Wisp?

▾

Wisp scores higher overall in our independent evaluation (73.6/100 vs 71.9/100), leading on value. Defy Medical comes out ahead on experience, product range, reputation.

Is Defy Medical or Wisp cheaper?

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Wisp has the lower starting price (from $5/mo vs $150/mo for Defy Medical). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Defy Medical and Wisp both offer?

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Both platforms treat Weight Loss / GLP-1, Sexual Health. Defy Medical covers 3 treatment categories total and Wisp covers 4.

Still deciding?

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