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DudeMeds vs He & She MD: Which Is Better?

Head-to-head comparison of DudeMeds and He & She MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

He & She MD scores higher overall in our independent evaluation (65.3/100 vs 59.7/100), leading on trust & safety, value, experience, product range. DudeMeds comes out ahead on reputation. DudeMeds has the lower entry price (from $39/mo vs $60/mo), so the better value depends on which treatment you need.

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DudeMeds is a Florida-based men's telehealth platform built around low-cost all-inclusive TRT that has expanded into GLP-1s, ED, hair loss, NAD+ and women's HRT.

Visit DudeMeds

He & She MD is a Newport Beach-based men's and women's telehealth brand covering GLP-1s, longevity injectables, HRT, testosterone, hair loss and ED, with the lowest prices tied to long prepaid terms.

Visit He & She MD

Score Breakdown

DimensionDudeMedsHe & She MD
Overall Score59.7/10065.3/100 ✓
Trust & Safety30%55/10058/100 ✓
Value25%70/10074/100 ✓
Experience20%45/10060/100 ✓
Product Range15%78/10084/100 ✓
Reputation10%50/100 ✓48/100

At a Glance

Founded20212025
HeadquartersFloridaNewport Beach, CA
Publicly tradedNoNo
Treatment categories77
Treatments listed513
Starting price$39/mo$60/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryDudeMedsHe & She MD
Hormone Therapy$77–$179
All-Inclusive TRT (testosterone cypionate)
$119
Testosterone (injection, gel, tablet)
Men's Health—$139
Enclomiphene
Sexual Health$39–$49
ED (generic sildenafil / tadalafil)
$60–$96
ED Treatment (on-demand, daily, combination)
Hair Loss—$76–$79
Hair Growth (oral/topical/combo, men and women)
Weight Loss / GLP-1$175–$199
Compounded Semaglutide
$99–$199
Compounded Semaglutide (injectable)
Longevity & Peptides—$100–$149
Glutathione
Women's Health——

DudeMeds

+All-inclusive TRT from $77/month bundles testosterone, estrogen blocker, supplies, labs and televisits, among the lowest headline TRT prices in telehealth
+Broad catalog under one account: TRT and enclomiphene, compounded and branded GLP-1s, ED, hair loss, NAD+ and LDN
+No separate membership or doctor fee on GLP-1 plans, with free shipping (per third-party pricing checks)
−Trustpilot 2.3/5 (11 reviews) with reports of unauthorized multi-month renewal charges and no company replies to negative reviews
−Patients report the member portal has been non-functional for months, plus refill delays and lost lab work
−GLP-1 pricing not published; third-party audit found the advertised $149/month entry price unavailable at checkout
Read the full DudeMeds review →

He & She MD

+Broad catalog covering compounded GLP-1s (injectable and oral), NAD+, sermorelin, glutathione, estradiol/progesterone HRT, testosterone, enclomiphene, hair loss and ED
+Names its dispensing pharmacies and the states where one partner cannot ship sterile compounds
+Low entry pricing on long terms: compounded semaglutide $99/mo on annual prepay, hair loss $79/mo, ED from $10/dose
−Site shows '4.8 Excellent' and 5.0 rating badges while its Trustpilot profile has zero reviews, so the ratings can't be verified
−Most headline prices require 3- to 12-month prepayment; month-to-month semaglutide is $199 and tirzepatide $299
−Platform terms allow a $15 fee per additional consult or lab-result interpretation on top of plan prices
Read the full He & She MD review →

DudeMeds vs He & She MD — FAQ

Is DudeMeds better than He & She MD?

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He & She MD scores higher overall in our independent evaluation (65.3/100 vs 59.7/100), leading on trust & safety, value, experience, product range. DudeMeds comes out ahead on reputation. DudeMeds has the lower entry price (from $39/mo vs $60/mo), so the better value depends on which treatment you need.

Is DudeMeds or He & She MD cheaper?

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DudeMeds has the lower starting price (from $39/mo vs $60/mo for He & She MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do DudeMeds and He & She MD both offer?

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Both platforms treat Hormone Therapy, Men's Health, Sexual Health, Hair Loss, Weight Loss / GLP-1, Longevity & Peptides, Women's Health. DudeMeds covers 7 treatment categories total and He & She MD covers 7.

Still deciding?