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Effecty vs Rex MD: Which Is Better?

Head-to-head comparison of Effecty and Rex MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Rex MD scores higher overall in our independent evaluation (72.2/100 vs 66.8/100), leading on trust & safety, product range, reputation. Effecty comes out ahead on value, experience.

67

New York-based cash-pay telehealth brand selling compounded GLP-1s, longevity injectables (NAD+, sermorelin, glutathione) and estradiol HRT with no membership fee and published tiered pricing.

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72
Rex MD
Good

Rex MD is a men's-health telehealth brand — owned by publicly traded LifeMD — covering ED, premature ejaculation, TRT, hair loss, and GLP-1 treatment.

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Score Breakdown

DimensionEffectyRex MD
Overall Score66.8/10072.2/100 ✓
Trust & Safety30%60/10078/100 ✓
Value25%76/100 ✓65/100
Experience20%72/100 ✓68/100
Product Range15%66/10078/100 ✓
Reputation10%55/10072/100 ✓

At a Glance

Founded20242019
HeadquartersNew York, NYNew York, NY
Publicly tradedNoNo
Treatment categories45
Treatments listed96
Starting price$55/mo$2/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEffectyRex MD
Weight Loss / GLP-1$80
Metformin
$199–$399
GLP-1 Weight Loss
Hormone Therapy$55–$180
Estradiol (tablet, cream or patch) + Progesterone
$79–$199
TRT (cypionate/gel/Clomid/sermorelin)

Effecty

+No membership fee, and prices are published per product and don't change with dose (semaglutide $130–$170/mo, tirzepatide $190–$235/mo)
+Card is held, not charged, until a prescription is written; shipping is free and expedited
+4.6/5 on Trustpilot across ~1,300 reviews, most citing fast support responses
−Only operating since November 2024; BBB rating is B with three closed complaints
−Visits are chat-only, and the compounding pharmacies are not named on the site
−Lowest advertised prices require 12-month prepayment; month-to-month runs 25–30% higher
Read the full Effecty review →

Rex MD

+Backed by LifeMD, a publicly traded parent company, giving it more financial and compliance infrastructure than an independent startup
+Strong Trustpilot rating (4.7/5, 5,259 reviews) with consistent praise for customer service staff
+Wide medication range across ED, premature ejaculation, TRT, hair loss, and GLP-1s under one account
−Recurring patient complaints about surprise auto-renewal charges not clearly disclosed at checkout
−Shipping and fulfillment issues reported, including incorrect dosing and underfilled vials
−Headline 'as low as $2/dose' pricing is a teaser rate; full pricing isn't shown until after intake
Read the full Rex MD review →

Effecty vs Rex MD — FAQ

Is Effecty better than Rex MD?

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Rex MD scores higher overall in our independent evaluation (72.2/100 vs 66.8/100), leading on trust & safety, product range, reputation. Effecty comes out ahead on value, experience.

Is Effecty or Rex MD cheaper?

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Rex MD has the lower starting price (from $2/mo vs $55/mo for Effecty). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Effecty and Rex MD both offer?

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Both platforms treat Weight Loss / GLP-1, Hormone Therapy. Effecty covers 4 treatment categories total and Rex MD covers 5.

Still deciding?

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