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Effecty vs RxSpan MD: Which Is Better?

Head-to-head comparison of Effecty and RxSpan MD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Effecty scores higher overall in our independent evaluation (66.8/100 vs 59.1/100), leading on value, experience, reputation. RxSpan MD comes out ahead on product range. RxSpan MD has the lower entry price (from $30/mo vs $55/mo), so the better value depends on which treatment you need.

67

New York-based cash-pay telehealth brand selling compounded GLP-1s, longevity injectables (NAD+, sermorelin, glutathione) and estradiol HRT with no membership fee and published tiered pricing.

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59

RxSpan MD is a Beverly Hills telehealth practice founded by a plastic surgeon, offering compounded and branded GLP-1s, longevity peptides, hair-loss and ED treatment.

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Score Breakdown

DimensionEffectyRxSpan MD
Overall Score66.8/100 ✓59.1/100
Trust & Safety30%60/10060/100
Value25%76/100 ✓58/100
Experience20%72/100 ✓52/100
Product Range15%66/10078/100 ✓
Reputation10%55/100 ✓45/100

At a Glance

Founded20242026
HeadquartersNew York, NYBeverly Hills, CA
Publicly tradedNoNo
Treatment categories44
Treatments listed99
Starting price$55/mo$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEffectyRxSpan MD
Weight Loss / GLP-1$80
Metformin
$249–$299
Compounded Semaglutide (injection or oral)
Longevity & Peptides$95–$150
Lipotropic (MIC) + B12
$100–$200
Glutathione

Effecty

+No membership fee, and prices are published per product and don't change with dose (semaglutide $130–$170/mo, tirzepatide $190–$235/mo)
+Card is held, not charged, until a prescription is written; shipping is free and expedited
+4.6/5 on Trustpilot across ~1,300 reviews, most citing fast support responses
−Only operating since November 2024; BBB rating is B with three closed complaints
−Visits are chat-only, and the compounding pharmacies are not named on the site
−Lowest advertised prices require 12-month prepayment; month-to-month runs 25–30% higher
Read the full Effecty review →

RxSpan MD

+Physician-founded practice with a named founder and a stated Beverly Hills address
+Offers both compounded (injection and oral) and branded GLP-1s, including cash-pay Zepbound listed at $500
+Third-party coverage reports named 503A pharmacy partners and free expedited shipping
−Compounded prices aren't visible on the public site; its product catalog failed to load during our research
−Brand-stated first-month prices ($249 semaglutide, $329 tirzepatide) are above peer averages, and renewal pricing is not published
−Site configuration shows an $80 initial visit fee that is not prominently disclosed
Read the full RxSpan MD review →

Effecty vs RxSpan MD — FAQ

Is Effecty better than RxSpan MD?

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Effecty scores higher overall in our independent evaluation (66.8/100 vs 59.1/100), leading on value, experience, reputation. RxSpan MD comes out ahead on product range. RxSpan MD has the lower entry price (from $30/mo vs $55/mo), so the better value depends on which treatment you need.

Is Effecty or RxSpan MD cheaper?

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RxSpan MD has the lower starting price (from $30/mo vs $55/mo for Effecty). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Effecty and RxSpan MD both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides. Effecty covers 4 treatment categories total and RxSpan MD covers 4.

Still deciding?

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