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Effecty vs System Labs: Which Is Better?

Head-to-head comparison of Effecty and System Labs based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Effecty scores higher overall in our independent evaluation (66.8/100 vs 56.4/100), leading on trust & safety, value, experience, product range, reputation.

67

New York-based cash-pay telehealth brand selling compounded GLP-1s, longevity injectables (NAD+, sermorelin, glutathione) and estradiol HRT with no membership fee and published tiered pricing.

Visit Effecty
56

System Labs is a San Francisco-based telehealth service prescribing compounded NAD+, sermorelin, glutathione and MIC-B12, with half-price first months.

Visit System Labs

Score Breakdown

DimensionEffectySystem Labs
Overall Score66.8/100 ✓56.4/100
Trust & Safety30%60/100 ✓52/100
Value25%76/100 ✓68/100
Experience20%72/100 ✓55/100
Product Range15%66/100 ✓55/100
Reputation10%55/100 ✓45/100

At a Glance

Founded2024—
HeadquartersNew York, NYSan Francisco, CA
Publicly tradedNoNo
Treatment categories41
Treatments listed96
Starting price$55/mo$89/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryEffectySystem Labs
Longevity & Peptides$95–$150
Lipotropic (MIC) + B12
$89
MIC+B12 Injection

Effecty

+No membership fee, and prices are published per product and don't change with dose (semaglutide $130–$170/mo, tirzepatide $190–$235/mo)
+Card is held, not charged, until a prescription is written; shipping is free and expedited
+4.6/5 on Trustpilot across ~1,300 reviews, most citing fast support responses
−Only operating since November 2024; BBB rating is B with three closed complaints
−Visits are chat-only, and the compounding pharmacies are not named on the site
−Lowest advertised prices require 12-month prepayment; month-to-month runs 25–30% higher
Read the full Effecty review →

System Labs

+Every price is posted on the site, including a first-month discount of roughly 40–50%
+Names its main compounding pharmacy (The Pharmacy Hub, Miami) and three board-certified physician advisors
+Both injectable and non-injectable options (NAD+ nasal spray, oral sermorelin)
−Trustpilot removed its business profile for guideline violations, so there is no independent review base
−'20k+ patients' claim is unverified; founding date and company history are not disclosed
−All sales are final once shipped; terms impose binding arbitration and a class-action waiver
Read the full System Labs review →

Effecty vs System Labs — FAQ

Is Effecty better than System Labs?

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Effecty scores higher overall in our independent evaluation (66.8/100 vs 56.4/100), leading on trust & safety, value, experience, product range, reputation.

Is Effecty or System Labs cheaper?

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Effecty has the lower starting price (from $55/mo vs $89/mo for System Labs). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Effecty and System Labs both offer?

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Both platforms treat Longevity & Peptides. Effecty covers 4 treatment categories total and System Labs covers 1.

Still deciding?

Effecty alternativesSystem Labs alternativesTake the Match Quiz