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He & She MD vs HealthRX: Which Is Better?

Head-to-head comparison of He & She MD and HealthRX based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

He & She MD scores higher overall in our independent evaluation (65.3/100 vs 59.3/100), leading on trust & safety, product range, reputation. HealthRX comes out ahead on value.

He & She MD is a Newport Beach-based men's and women's telehealth brand covering GLP-1s, longevity injectables, HRT, testosterone, hair loss and ED, with the lowest prices tied to long prepaid terms.

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HealthRX.com is a compounded-GLP-1 telehealth marketplace. It sells semaglutide at $165/mo and tirzepatide at $214/mo at every dose, and backs its program with a weight-loss money-back guarantee.

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Score Breakdown

DimensionHe & She MDHealthRX
Overall Score65.3/100 ✓59.3/100
Trust & Safety30%58/100 ✓55/100
Value25%74/10078/100 ✓
Experience20%60/10060/100
Product Range15%84/100 ✓45/100
Reputation10%48/100 ✓45/100

At a Glance

Founded20252023
HeadquartersNewport Beach, CA—
Publicly tradedNoNo
Treatment categories71
Treatments listed132
Starting price$60/mo$99/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHe & She MDHealthRX
Weight Loss / GLP-1$99–$199
Compounded Semaglutide (injectable)
$99–$165
Compounded Semaglutide

He & She MD

+Broad catalog covering compounded GLP-1s (injectable and oral), NAD+, sermorelin, glutathione, estradiol/progesterone HRT, testosterone, enclomiphene, hair loss and ED
+Names its dispensing pharmacies and the states where one partner cannot ship sterile compounds
+Low entry pricing on long terms: compounded semaglutide $99/mo on annual prepay, hair loss $79/mo, ED from $10/dose
−Site shows '4.8 Excellent' and 5.0 rating badges while its Trustpilot profile has zero reviews, so the ratings can't be verified
−Most headline prices require 3- to 12-month prepayment; month-to-month semaglutide is $199 and tirzepatide $299
−Platform terms allow a $15 fee per additional consult or lab-result interpretation on top of plan prices
Read the full He & She MD review →

HealthRX

+Flat pricing at every dose: semaglutide $165/mo ($149 first month) and tirzepatide $214/mo ($193 first month); about $99/mo semaglutide on a 12-month plan
+Physician review within 24 hours, overnight cold-chain shipping included, and a full refund if not prescribed
+Weight-loss money-back guarantee (reported terms: 16+ weeks on treatment, 10% loss threshold)
−Operating company, headquarters, medical group and dispensing pharmacy are not named; terms reference only a San Diego dispute venue
−Guarantee measurement and refund mechanics are not fully published
−Thin independent review footprint for a brand active since about 2023
Read the full HealthRX review →

He & She MD vs HealthRX — FAQ

Is He & She MD better than HealthRX?

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He & She MD scores higher overall in our independent evaluation (65.3/100 vs 59.3/100), leading on trust & safety, product range, reputation. HealthRX comes out ahead on value.

Is He & She MD or HealthRX cheaper?

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He & She MD has the lower starting price (from $60/mo vs $99/mo for HealthRX). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do He & She MD and HealthRX both offer?

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Both platforms treat Weight Loss / GLP-1. He & She MD covers 7 treatment categories total and HealthRX covers 1.

Still deciding?