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He & She MD vs LifeMD: Which Is Better?

Head-to-head comparison of He & She MD and LifeMD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

LifeMD scores higher overall in our independent evaluation (68/100 vs 65.3/100), leading on trust & safety, value, experience, reputation. He & She MD comes out ahead on product range.

He & She MD is a Newport Beach-based men's and women's telehealth brand covering GLP-1s, longevity injectables, HRT, testosterone, hair loss and ED, with the lowest prices tied to long prepaid terms.

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68
LifeMD
Good

Publicly traded telehealth betting big on weight loss, with aggressive GLP-1 pricing and fast-growing subscriber base.

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Score Breakdown

DimensionHe & She MDLifeMD
Overall Score65.3/10068/100 ✓
Trust & Safety30%58/10065/100 ✓
Value25%74/10075/100 ✓
Experience20%60/10070/100 ✓
Product Range15%84/100 ✓65/100
Reputation10%48/10060/100 ✓

At a Glance

Founded20252020
HeadquartersNewport Beach, CANew York, NY
Publicly tradedNoYes (LFMD)
Treatment categories76
Treatments listed135
Starting price$60/mo$14/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHe & She MDLifeMD
Weight Loss / GLP-1$99–$199
Compounded Semaglutide (injectable)
$149–$349
Branded Wegovy (oral/injectable)
Hormone Therapy$119
Testosterone (injection, gel, tablet)
$99
Testosterone Program (via Rex MD)
Men's Health$139
Enclomiphene
—
Hair Loss$76–$79
Hair Growth (oral/topical/combo, men and women)
$14–$27
Finasteride (via Rex MD)
Sexual Health$60–$96
ED Treatment (on-demand, daily, combination)
$14–$38
Sildenafil (via Rex MD)

He & She MD

+Broad catalog covering compounded GLP-1s (injectable and oral), NAD+, sermorelin, glutathione, estradiol/progesterone HRT, testosterone, enclomiphene, hair loss and ED
+Names its dispensing pharmacies and the states where one partner cannot ship sterile compounds
+Low entry pricing on long terms: compounded semaglutide $99/mo on annual prepay, hair loss $79/mo, ED from $10/dose
−Site shows '4.8 Excellent' and 5.0 rating badges while its Trustpilot profile has zero reviews, so the ratings can't be verified
−Most headline prices require 3- to 12-month prepayment; month-to-month semaglutide is $199 and tirzepatide $299
−Platform terms allow a $15 fee per additional consult or lab-result interpretation on top of plan prices
Read the full He & She MD review →

LifeMD

+Novo Nordisk partnership for branded Wegovy pill and subscription program
+Eli Lilly partnership for branded Zepbound access
+Publicly traded with quarterly earnings transparency — 25% revenue growth in 2025
−Compounded GLP-1s discontinued — pivoted to branded medications
−Aggressive marketing draws scrutiny from health professionals
−Narrower treatment range than Hims or Ro
Read the full LifeMD review →

He & She MD vs LifeMD — FAQ

Is He & She MD better than LifeMD?

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LifeMD scores higher overall in our independent evaluation (68/100 vs 65.3/100), leading on trust & safety, value, experience, reputation. He & She MD comes out ahead on product range.

Is He & She MD or LifeMD cheaper?

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LifeMD has the lower starting price (from $14/mo vs $60/mo for He & She MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do He & She MD and LifeMD both offer?

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Both platforms treat Weight Loss / GLP-1, Hormone Therapy, Men's Health, Hair Loss, Sexual Health. He & She MD covers 7 treatment categories total and LifeMD covers 6.

Still deciding?