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He & She MD vs MadeMed: Which Is Better?

Head-to-head comparison of He & She MD and MadeMed based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

He & She MD scores higher overall in our independent evaluation (65.3/100 vs 57.3/100), leading on trust & safety, value, experience, product range, reputation. MadeMed has the lower entry price (from $30/mo vs $60/mo), so the better value depends on which treatment you need.

He & She MD

Good

He & She MD is a Newport Beach-based men's and women's telehealth brand covering GLP-1s, longevity injectables, HRT, testosterone, hair loss and ED, with the lowest prices tied to long prepaid terms.

Visit He & She MD

MadeMed

Fair

MadeMed is a Houston-registered telehealth brand selling compounded injectable and oral GLP-1s, sermorelin, NAD+ and tadalafil through the Xpedicare provider network.

Visit MadeMed

Score Breakdown

Dimension	He & She MD	MadeMed
Overall Score	65.3/100 ✓	57.3/100
Trust & Safety30%	58/100 ✓	55/100
Value25%	74/100 ✓	66/100
Experience20%	60/100 ✓	45/100
Product Range15%	84/100 ✓	72/100
Reputation10%	48/100 ✓	45/100

At a Glance

Founded	2025	—
Headquarters	Newport Beach, CA	Houston, TX
Publicly traded	No	No
Treatment categories	7	3
Treatments listed	13	7
Starting price	$60/mo	$30/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

Category	He & She MD	MadeMed
Weight Loss / GLP-1	$99–$199 Compounded Semaglutide (injectable)	$99–$199 Compounded Semaglutide (injectable)
Longevity & Peptides	$100–$149 Glutathione	$129–$229 Sermorelin (injectable or oral)
Sexual Health	$60–$96 ED Treatment (on-demand, daily, combination)	$30–$90 Tadalafil

He & She MD

+Broad catalog covering compounded GLP-1s (injectable and oral), NAD+, sermorelin, glutathione, estradiol/progesterone HRT, testosterone, enclomiphene, hair loss and ED

+Names its dispensing pharmacies and the states where one partner cannot ship sterile compounds

+Low entry pricing on long terms: compounded semaglutide $99/mo on annual prepay, hair loss $79/mo, ED from $10/dose

−Site shows '4.8 Excellent' and 5.0 rating badges while its Trustpilot profile has zero reviews, so the ratings can't be verified

−Most headline prices require 3- to 12-month prepayment; month-to-month semaglutide is $199 and tirzepatide $299

−Platform terms allow a $15 fee per additional consult or lab-result interpretation on top of plan prices

Read the full He & She MD review →

MadeMed

+Offers both injectable and oral/sublingual versions of semaglutide, tirzepatide and sermorelin, plus NAD+ as injection or nasal spray

+Operating entity, provider network (Xpedicare) and a partner pharmacy (Red Rock) are named in the terms and About page

+Advertised GLP-1 entry pricing from $99/mo is at the low end of the market

−Product pages showed no pricing or product detail during our research, in a direct fetch or a real browser

−Advertised prices and state coverage (about 40 states) come from brand-issued press releases and can't be verified on-site

−No Trustpilot or other independent patient reviews; public coverage is mostly paid newswire content

Read the full MadeMed review →

He & She MD vs MadeMed — FAQ

Is He & She MD better than MadeMed?

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Is He & She MD or MadeMed cheaper?

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MadeMed has the lower starting price (from $30/mo vs $60/mo for He & She MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do He & She MD and MadeMed both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides, Sexual Health. He & She MD covers 7 treatment categories total and MadeMed covers 3.

Still deciding?

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