He & She MD vs ProlongMD: Which Is Better?
Head-to-head comparison of He & She MD and ProlongMD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.
Our Verdict
He & She MD scores higher overall in our independent evaluation (65.3/100 vs 60.1/100), leading on trust & safety, experience, product range, reputation. ProlongMD has the lower entry price (from $25/mo vs $60/mo), so the better value depends on which treatment you need.
He & She MD is a Newport Beach-based men's and women's telehealth brand covering GLP-1s, longevity injectables, HRT, testosterone, hair loss and ED, with the lowest prices tied to long prepaid terms.
Visit He & She MDSmall, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.
Visit ProlongMDScore Breakdown
| Dimension | He & She MD | ProlongMD |
|---|---|---|
| Overall Score | 65.3/100 ✓ | 60.1/100 |
| Trust & Safety30% | 58/100 ✓ | 52/100 |
| Value25% | 74/100 | 74/100 |
| Experience20% | 60/100 ✓ | 55/100 |
| Product Range15% | 84/100 ✓ | 70/100 |
| Reputation10% | 48/100 ✓ | 45/100 |
At a Glance
| Founded | 2025 | 2025 |
| Headquarters | Newport Beach, CA | Phoenix, AZ |
| Publicly traded | No | No |
| Treatment categories | 7 | 8 |
| Treatments listed | 13 | 13 |
| Starting price | $60/mo | $25/mo |
Pricing Where They Compete
Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.
| Category | He & She MD | ProlongMD |
|---|---|---|
| Weight Loss / GLP-1 | $99–$199 Compounded Semaglutide (injectable) | $99–$119 Compounded Semaglutide/B12 |
| Longevity & Peptides | $100–$149 Glutathione | $179 Sermorelin |
| Hormone Therapy | $119 Testosterone (injection, gel, tablet) | $89–$119 Testosterone Cypionate (200 mg/mL) |
| Women's Health | — | $33 Progesterone (oral) |
| Men's Health | $139 Enclomiphene | $129–$159 Enclomiphene 25 mg |
| Hair Loss | $76–$79 Hair Growth (oral/topical/combo, men and women) | $25 Oral Finasteride 5 mg |
| Sexual Health | $60–$96 ED Treatment (on-demand, daily, combination) | $75 Tadalafil 24 mg |
He & She MD
ProlongMD
He & She MD vs ProlongMD — FAQ
Is He & She MD better than ProlongMD?
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He & She MD scores higher overall in our independent evaluation (65.3/100 vs 60.1/100), leading on trust & safety, experience, product range, reputation. ProlongMD has the lower entry price (from $25/mo vs $60/mo), so the better value depends on which treatment you need.
Is He & She MD or ProlongMD cheaper?
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ProlongMD has the lower starting price (from $25/mo vs $60/mo for He & She MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.
What do He & She MD and ProlongMD both offer?
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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides, Hormone Therapy, Women's Health, Men's Health, Hair Loss, Sexual Health. He & She MD covers 7 treatment categories total and ProlongMD covers 8.
Still deciding?