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He & She MD vs Shameless Care: Which Is Better?

Head-to-head comparison of He & She MD and Shameless Care based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Shameless Care scores higher overall in our independent evaluation (66/100 vs 65.3/100), leading on trust & safety, experience, reputation. He & She MD comes out ahead on value, product range. He & She MD has the lower entry price (from $60/mo vs $63/mo), so the better value depends on which treatment you need.

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He & She MD is a Newport Beach-based men's and women's telehealth brand covering GLP-1s, longevity injectables, HRT, testosterone, hair loss and ED, with the lowest prices tied to long prepaid terms.

Visit He & She MD
66

Shameless Care is an Illinois sexual-health telehealth company selling ED and female-arousal medications, comprehensive STI testing, DoxyPEP and UTI/BV/yeast treatment as one-time purchases.

Visit Shameless Care

Score Breakdown

DimensionHe & She MDShameless Care
Overall Score65.3/10066/100 ✓
Trust & Safety30%58/10068/100 ✓
Value25%74/100 ✓68/100
Experience20%60/10066/100 ✓
Product Range15%84/100 ✓66/100
Reputation10%48/10055/100 ✓

At a Glance

Founded20252022
HeadquartersNewport Beach, CASt. Charles, IL
Publicly tradedNoNo
Treatment categories74
Treatments listed1310
Starting price$60/mo$63/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHe & She MDShameless Care
Women's Health—$63
UTI / BV / Yeast Infection Treatment
Men's Health$139
Enclomiphene
—
Sexual Health$60–$96
ED Treatment (on-demand, daily, combination)
$99–$199
DoxyPEP

He & She MD

+Broad catalog covering compounded GLP-1s (injectable and oral), NAD+, sermorelin, glutathione, estradiol/progesterone HRT, testosterone, enclomiphene, hair loss and ED
+Names its dispensing pharmacies and the states where one partner cannot ship sterile compounds
+Low entry pricing on long terms: compounded semaglutide $99/mo on annual prepay, hair loss $79/mo, ED from $10/dose
−Site shows '4.8 Excellent' and 5.0 rating badges while its Trustpilot profile has zero reviews, so the ratings can't be verified
−Most headline prices require 3- to 12-month prepayment; month-to-month semaglutide is $199 and tirzepatide $299
−Platform terms allow a $15 fee per additional consult or lab-result interpretation on top of plan prices
Read the full He & She MD review →

Shameless Care

+One-time purchases with no auto-renewal, which avoids the recurring-charge complaints common in the category
+Every price is posted on the site, all-in with consult, prescription and shipping (e.g. UTI treatment $63, Shameless Duo from $130)
+Covers men's and women's sexual health, including STI testing, DoxyPEP, herpes suppression and female arousal treatments, which most ED-focused brands don't
−Two of its three named partner pharmacies (Curexa, Belmar) received FDA compounding warning letters in 2023
−Review evidence is mostly the brand's own on-site testimonials; little independent Trustpilot or Reddit footprint
−Compounded ED troches cost about $7–11 per dose, well above generic sildenafil or tadalafil tablets
Read the full Shameless Care review →

He & She MD vs Shameless Care — FAQ

Is He & She MD better than Shameless Care?

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Shameless Care scores higher overall in our independent evaluation (66/100 vs 65.3/100), leading on trust & safety, experience, reputation. He & She MD comes out ahead on value, product range. He & She MD has the lower entry price (from $60/mo vs $63/mo), so the better value depends on which treatment you need.

Is He & She MD or Shameless Care cheaper?

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He & She MD has the lower starting price (from $60/mo vs $63/mo for Shameless Care). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do He & She MD and Shameless Care both offer?

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Both platforms treat Women's Health, Men's Health, Sexual Health. He & She MD covers 7 treatment categories total and Shameless Care covers 4.

Still deciding?

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