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He & She MD vs SkinnyRx: Which Is Better?

Head-to-head comparison of He & She MD and SkinnyRx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

He & She MD scores higher overall in our independent evaluation (65.3/100 vs 57.9/100), leading on trust & safety, value, product range, reputation. SkinnyRx comes out ahead on experience.

65

He & She MD is a Newport Beach-based men's and women's telehealth brand covering GLP-1s, longevity injectables, HRT, testosterone, hair loss and ED, with the lowest prices tied to long prepaid terms.

Visit He & She MD
58

Cash-pay compounded GLP-1 provider offering five dosing formats, currently facing an FDA warning letter against its parent company.

Visit SkinnyRx

Score Breakdown

DimensionHe & She MDSkinnyRx
Overall Score65.3/100 ✓57.9/100
Trust & Safety30%58/100 ✓45/100
Value25%74/100 ✓68/100
Experience20%60/10078/100 ✓
Product Range15%84/100 ✓55/100
Reputation10%48/100 ✓35/100

At a Glance

Founded2025—
HeadquartersNewport Beach, CA—
Publicly tradedNoNo
Treatment categories71
Treatments listed134
Starting price$60/mo$199/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHe & She MDSkinnyRx
Weight Loss / GLP-1$99–$199
Compounded Semaglutide (injectable)
$199
Semaglutide Injection

He & She MD

+Broad catalog covering compounded GLP-1s (injectable and oral), NAD+, sermorelin, glutathione, estradiol/progesterone HRT, testosterone, enclomiphene, hair loss and ED
+Names its dispensing pharmacies and the states where one partner cannot ship sterile compounds
+Low entry pricing on long terms: compounded semaglutide $99/mo on annual prepay, hair loss $79/mo, ED from $10/dose
−Site shows '4.8 Excellent' and 5.0 rating badges while its Trustpilot profile has zero reviews, so the ratings can't be verified
−Most headline prices require 3- to 12-month prepayment; month-to-month semaglutide is $199 and tirzepatide $299
−Platform terms allow a $15 fee per additional consult or lab-result interpretation on top of plan prices
Read the full He & She MD review →

SkinnyRx

+Five dosing formats (injection, sublingual, tablet) for semaglutide/tirzepatide give patients flexibility
+Large Trustpilot volume (5,390 reviews) at a 4.8 average suggests broad satisfaction
+Reps cited by name in reviews for responsive onboarding guidance
−FDA warning letter reportedly issued to parent company Lean Rx, Inc. (February 2026) — unverified independently this cycle, needs manual confirmation
−Some patients report oral/sublingual formats were ineffective with no visible results
−A reviewer described being required to pay upfront for medication that had no effect
Read the full SkinnyRx review →

He & She MD vs SkinnyRx — FAQ

Is He & She MD better than SkinnyRx?

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He & She MD scores higher overall in our independent evaluation (65.3/100 vs 57.9/100), leading on trust & safety, value, product range, reputation. SkinnyRx comes out ahead on experience.

Is He & She MD or SkinnyRx cheaper?

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He & She MD has the lower starting price (from $60/mo vs $199/mo for SkinnyRx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do He & She MD and SkinnyRx both offer?

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Both platforms treat Weight Loss / GLP-1. He & She MD covers 7 treatment categories total and SkinnyRx covers 1.

Still deciding?

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