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He & She MD vs TrimRx: Which Is Better?

Head-to-head comparison of He & She MD and TrimRx based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

He & She MD scores higher overall in our independent evaluation (65.3/100 vs 52/100), leading on trust & safety, value, experience, product range, reputation.

65

He & She MD is a Newport Beach-based men's and women's telehealth brand covering GLP-1s, longevity injectables, HRT, testosterone, hair loss and ED, with the lowest prices tied to long prepaid terms.

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52
TrimRx
Below Average

San Diego-based GLP-1 weight loss telehealth offering compounded semaglutide and tirzepatide at $179-349/month.

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Score Breakdown

DimensionHe & She MDTrimRx
Overall Score65.3/100 ✓52/100
Trust & Safety30%58/100 ✓55/100
Value25%74/100 ✓70/100
Experience20%60/100 ✓45/100
Product Range15%84/100 ✓30/100
Reputation10%48/100 ✓45/100

At a Glance

Founded20252024
HeadquartersNewport Beach, CASan Diego, CA
Publicly tradedNoNo
Treatment categories71
Treatments listed138
Starting price$60/mo$179/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHe & She MDTrimRx
Weight Loss / GLP-1$99–$199
Compounded Semaglutide (injectable)
$179–$329
Compounded Semaglutide (Oral/Sublingual)

He & She MD

+Broad catalog covering compounded GLP-1s (injectable and oral), NAD+, sermorelin, glutathione, estradiol/progesterone HRT, testosterone, enclomiphene, hair loss and ED
+Names its dispensing pharmacies and the states where one partner cannot ship sterile compounds
+Low entry pricing on long terms: compounded semaglutide $99/mo on annual prepay, hair loss $79/mo, ED from $10/dose
−Site shows '4.8 Excellent' and 5.0 rating badges while its Trustpilot profile has zero reviews, so the ratings can't be verified
−Most headline prices require 3- to 12-month prepayment; month-to-month semaglutide is $199 and tirzepatide $299
−Platform terms allow a $15 fee per additional consult or lab-result interpretation on top of plan prices
Read the full He & She MD review →

TrimRx

+70-85% savings vs brand-name GLP-1s: semaglutide at $199/mo vs $1,000+ retail
+Not included in FDA's 2025 warning letter wave — clean regulatory record
+Multiple delivery formats: injectable, oral tablet, and sublingual drops
−Branded pages advertise 'In Stock' with a price while the same page states TrimRx does not sell, dispense or ship branded medication and the patient pays a pharmacy directly
−Cancellation difficulties: long phone waits, reports of being hung up on; dedicated JoinChargeback page exists
−Strict no-refund policy once medical intake is submitted, even before medication ships
Read the full TrimRx review →

He & She MD vs TrimRx — FAQ

Is He & She MD better than TrimRx?

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He & She MD scores higher overall in our independent evaluation (65.3/100 vs 52/100), leading on trust & safety, value, experience, product range, reputation.

Is He & She MD or TrimRx cheaper?

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He & She MD has the lower starting price (from $60/mo vs $179/mo for TrimRx). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do He & She MD and TrimRx both offer?

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Both platforms treat Weight Loss / GLP-1. He & She MD covers 7 treatment categories total and TrimRx covers 1.

Still deciding?

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