He & She MD vs Twentyeight Health: Which Is Better?
Head-to-head comparison of He & She MD and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.
Our Verdict
Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 65.3/100), leading on trust & safety, value, experience, reputation. He & She MD comes out ahead on product range.
He & She MD is a Newport Beach-based men's and women's telehealth brand covering GLP-1s, longevity injectables, HRT, testosterone, hair loss and ED, with the lowest prices tied to long prepaid terms.
Visit He & She MDBrooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).
Visit Twentyeight HealthScore Breakdown
| Dimension | He & She MD | Twentyeight Health |
|---|---|---|
| Overall Score | 65.3/100 | 75/100 ✓ |
| Trust & Safety30% | 58/100 | 76/100 ✓ |
| Value25% | 74/100 | 80/100 ✓ |
| Experience20% | 60/100 | 72/100 ✓ |
| Product Range15% | 84/100 ✓ | 72/100 |
| Reputation10% | 48/100 | 70/100 ✓ |
At a Glance
| Founded | 2025 | 2018 |
| Headquarters | Newport Beach, CA | Brooklyn, NY |
| Publicly traded | No | No |
| Treatment categories | 7 | 4 |
| Treatments listed | 13 | 7 |
| Starting price | $60/mo | $15/mo |
Pricing Where They Compete
Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.
| Category | He & She MD | Twentyeight Health |
|---|---|---|
| Weight Loss / GLP-1 | $99–$199 Compounded Semaglutide (injectable) | — |
| Women's Health | — | $15–$19.99 Complete Care Membership |
| Sexual Health | $60–$96 ED Treatment (on-demand, daily, combination) | — |
He & She MD
Twentyeight Health
He & She MD vs Twentyeight Health — FAQ
Is He & She MD better than Twentyeight Health?
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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 65.3/100), leading on trust & safety, value, experience, reputation. He & She MD comes out ahead on product range.
Is He & She MD or Twentyeight Health cheaper?
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Twentyeight Health has the lower starting price (from $15/mo vs $60/mo for He & She MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.
What do He & She MD and Twentyeight Health both offer?
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Both platforms treat Weight Loss / GLP-1, Women's Health, Sexual Health. He & She MD covers 7 treatment categories total and Twentyeight Health covers 4.
Still deciding?