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He & She MD vs Wellmedr: Which Is Better?

Head-to-head comparison of He & She MD and Wellmedr based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

He & She MD scores higher overall in our independent evaluation (65.3/100 vs 60.8/100), leading on trust & safety, experience, product range, reputation. Wellmedr comes out ahead on value. Wellmedr has the lower entry price (from $40/mo vs $60/mo), so the better value depends on which treatment you need.

He & She MD is a Newport Beach-based men's and women's telehealth brand covering GLP-1s, longevity injectables, HRT, testosterone, hair loss and ED, with the lowest prices tied to long prepaid terms.

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Wellmedr is a St. Petersburg, FL telehealth brand launched in 2025. It sells low-priced compounded semaglutide and tirzepatide plus ED, enclomiphene, hair-loss and NAD+ treatments, prescribed through OpenLoop Health.

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Score Breakdown

DimensionHe & She MDWellmedr
Overall Score65.3/100 ✓60.8/100
Trust & Safety30%58/100 ✓50/100
Value25%74/10078/100 ✓
Experience20%60/100 ✓55/100
Product Range15%84/100 ✓72/100
Reputation10%48/100 ✓45/100

At a Glance

Founded20252025
HeadquartersNewport Beach, CASt. Petersburg, FL
Publicly tradedNoNo
Treatment categories76
Treatments listed136
Starting price$60/mo$40/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHe & She MDWellmedr
Weight Loss / GLP-1$99–$199
Compounded Semaglutide (injectable)
$49–$149
Compounded Semaglutide (+NAD+/B12)
Longevity & Peptides$100–$149
Glutathione
$120–$200
NAD+
Hormone Therapy$119
Testosterone (injection, gel, tablet)
$80–$150
Enclomiphene + Anastrozole
Men's Health$139
Enclomiphene
—
Hair Loss$76–$79
Hair Growth (oral/topical/combo, men and women)
$40–$80
4-in-1 Hair Formula (oral minoxidil/finasteride/biotin)
Sexual Health$60–$96
ED Treatment (on-demand, daily, combination)
$60–$120
Black Pill 3-in-1 (sildenafil/tadalafil/apomorphine)

He & She MD

+Broad catalog covering compounded GLP-1s (injectable and oral), NAD+, sermorelin, glutathione, estradiol/progesterone HRT, testosterone, enclomiphene, hair loss and ED
+Names its dispensing pharmacies and the states where one partner cannot ship sterile compounds
+Low entry pricing on long terms: compounded semaglutide $99/mo on annual prepay, hair loss $79/mo, ED from $10/dose
−Site shows '4.8 Excellent' and 5.0 rating badges while its Trustpilot profile has zero reviews, so the ratings can't be verified
−Most headline prices require 3- to 12-month prepayment; month-to-month semaglutide is $199 and tirzepatide $299
−Platform terms allow a $15 fee per additional consult or lab-result interpretation on top of plan prices
Read the full He & She MD review →

Wellmedr

+Some of the lowest compounded GLP-1 prices we track: $49/mo semaglutide and $89/mo tirzepatide on 12-month plans, the same at every dose
+Broad catalog for a new brand, spanning GLP-1s, a 3-in-1 ED pill, enclomiphene, a 4-in-1 hair-loss formula and NAD+
+Unlimited clinician messaging and 1–4 hour approval target; 90-day money-back guarantee advertised
−BBB rating of F with 75 complaints since its May 2025 start; BBB flagged a pattern of late or temperature-mishandled deliveries, charges after cancellation and refused guarantee refunds
−Reviewers report billing every 21 days rather than monthly, which adds charges over a year
−Dispensing pharmacies are not named, and prescribing is outsourced to OpenLoop Health and 'other networks'
Read the full Wellmedr review →

He & She MD vs Wellmedr — FAQ

Is He & She MD better than Wellmedr?

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He & She MD scores higher overall in our independent evaluation (65.3/100 vs 60.8/100), leading on trust & safety, experience, product range, reputation. Wellmedr comes out ahead on value. Wellmedr has the lower entry price (from $40/mo vs $60/mo), so the better value depends on which treatment you need.

Is He & She MD or Wellmedr cheaper?

▾

Wellmedr has the lower starting price (from $40/mo vs $60/mo for He & She MD). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do He & She MD and Wellmedr both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides, Hormone Therapy, Men's Health, Hair Loss, Sexual Health. He & She MD covers 7 treatment categories total and Wellmedr covers 6.

Still deciding?