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He & She MD vs XYON Health: Which Is Better?

Head-to-head comparison of He & She MD and XYON Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

XYON Health scores higher overall in our independent evaluation (65.9/100 vs 65.3/100), leading on trust & safety, experience, reputation. He & She MD comes out ahead on value, product range. He & She MD has the lower entry price (from $60/mo vs $109/mo), so the better value depends on which treatment you need.

He & She MD is a Newport Beach-based men's and women's telehealth brand covering GLP-1s, longevity injectables, HRT, testosterone, hair loss and ED, with the lowest prices tied to long prepaid terms.

Visit He & She MD

Physician-led hair loss telehealth brand co-founded by hair transplant surgeons, specializing in topical finasteride and combination scalp formulas.

Visit XYON Health

Score Breakdown

DimensionHe & She MDXYON Health
Overall Score65.3/10065.9/100 ✓
Trust & Safety30%58/10068/100 ✓
Value25%74/100 ✓62/100
Experience20%60/10064/100 ✓
Product Range15%84/100 ✓68/100
Reputation10%48/10070/100 ✓

At a Glance

Founded20252019
HeadquartersNewport Beach, CAVancouver, BC, Canada
Publicly tradedNoNo
Treatment categories73
Treatments listed133
Starting price$60/mo$109/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHe & She MDXYON Health
Women's Health——
Men's Health$139
Enclomiphene
—
Hair Loss$76–$79
Hair Growth (oral/topical/combo, men and women)
$109–$119
Topical Finasteride Gel

He & She MD

+Broad catalog covering compounded GLP-1s (injectable and oral), NAD+, sermorelin, glutathione, estradiol/progesterone HRT, testosterone, enclomiphene, hair loss and ED
+Names its dispensing pharmacies and the states where one partner cannot ship sterile compounds
+Low entry pricing on long terms: compounded semaglutide $99/mo on annual prepay, hair loss $79/mo, ED from $10/dose
−Site shows '4.8 Excellent' and 5.0 rating badges while its Trustpilot profile has zero reviews, so the ratings can't be verified
−Most headline prices require 3- to 12-month prepayment; month-to-month semaglutide is $199 and tirzepatide $299
−Platform terms allow a $15 fee per additional consult or lab-result interpretation on top of plan prices
Read the full He & She MD review →

XYON Health

+Co-founded by established hair transplant surgeons, lending clinical credibility to formulation choices
+One of the most-discussed topical finasteride brands in the r/tressless community
+Broad hair-loss formulation range: topical finasteride, topical dutasteride, combination gel, and oral options
−Small Trustpilot sample (65 reviews) limits confidence in the 3.7/5 rating
−Topical gel texture ('sticky,' hard to apply) is a recurring patient complaint
−No live communication channel with prescribing clinicians reported by several patients
Read the full XYON Health review →

He & She MD vs XYON Health — FAQ

Is He & She MD better than XYON Health?

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XYON Health scores higher overall in our independent evaluation (65.9/100 vs 65.3/100), leading on trust & safety, experience, reputation. He & She MD comes out ahead on value, product range. He & She MD has the lower entry price (from $60/mo vs $109/mo), so the better value depends on which treatment you need.

Is He & She MD or XYON Health cheaper?

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He & She MD has the lower starting price (from $60/mo vs $109/mo for XYON Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do He & She MD and XYON Health both offer?

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Both platforms treat Women's Health, Men's Health, Hair Loss. He & She MD covers 7 treatment categories total and XYON Health covers 3.

Still deciding?