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He & She MD vs Yucca Health: Which Is Better?

Head-to-head comparison of He & She MD and Yucca Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Yucca Health scores higher overall in our independent evaluation (68.3/100 vs 65.3/100), leading on trust & safety, value, experience, reputation. He & She MD comes out ahead on product range. He & She MD has the lower entry price (from $60/mo vs $125/mo), so the better value depends on which treatment you need.

He & She MD is a Newport Beach-based men's and women's telehealth brand covering GLP-1s, longevity injectables, HRT, testosterone, hair loss and ED, with the lowest prices tied to long prepaid terms.

Visit He & She MD

Yucca Health is a Beverly Hills-based telehealth platform selling compounded semaglutide and tirzepatide at flat, dose-independent prices, plus compounded NAD+ and sermorelin.

Visit Yucca Health

Score Breakdown

DimensionHe & She MDYucca Health
Overall Score65.3/10068.3/100 ✓
Trust & Safety30%58/10064/100 ✓
Value25%74/10080/100 ✓
Experience20%60/10072/100 ✓
Product Range15%84/100 ✓58/100
Reputation10%48/10060/100 ✓

At a Glance

Founded20252025
HeadquartersNewport Beach, CABeverly Hills, CA
Publicly tradedNoNo
Treatment categories72
Treatments listed134
Starting price$60/mo$125/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHe & She MDYucca Health
Weight Loss / GLP-1$99–$199
Compounded Semaglutide (injectable)
$125–$146
Compounded Semaglutide+ (injectable)
Longevity & Peptides$100–$149
Glutathione
$158–$215
NAD+ Injection

He & She MD

+Broad catalog covering compounded GLP-1s (injectable and oral), NAD+, sermorelin, glutathione, estradiol/progesterone HRT, testosterone, enclomiphene, hair loss and ED
+Names its dispensing pharmacies and the states where one partner cannot ship sterile compounds
+Low entry pricing on long terms: compounded semaglutide $99/mo on annual prepay, hair loss $79/mo, ED from $10/dose
−Site shows '4.8 Excellent' and 5.0 rating badges while its Trustpilot profile has zero reviews, so the ratings can't be verified
−Most headline prices require 3- to 12-month prepayment; month-to-month semaglutide is $199 and tirzepatide $299
−Platform terms allow a $15 fee per additional consult or lab-result interpretation on top of plan prices
Read the full He & She MD review →

Yucca Health

+Full price grid published before intake: semaglutide $146/mo monthly, $140/mo quarterly or $125/mo on a 6-month prepay; tirzepatide $258, $248 or $225/mo
+Locked pricing covers the whole dose range, so titrating up does not raise the bill; pausing keeps the locked rate
+No separate membership or consultation fee; plans include the provider consult, medication, injection supplies and free 2-day shipping
−Dispensing pharmacies are not named on the public site; they appear only in the patient portal and on the label after ordering
−BBB rating of C+ (not accredited) with five closed complaints; one Trustpilot reviewer reports prepaying six months and receiving three
−About 6% of roughly 1,230 Trustpilot reviews are 1-star, citing lack of results after months of treatment and refund disputes
Read the full Yucca Health review →

He & She MD vs Yucca Health — FAQ

Is He & She MD better than Yucca Health?

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Yucca Health scores higher overall in our independent evaluation (68.3/100 vs 65.3/100), leading on trust & safety, value, experience, reputation. He & She MD comes out ahead on product range. He & She MD has the lower entry price (from $60/mo vs $125/mo), so the better value depends on which treatment you need.

Is He & She MD or Yucca Health cheaper?

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He & She MD has the lower starting price (from $60/mo vs $125/mo for Yucca Health). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do He & She MD and Yucca Health both offer?

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Both platforms treat Weight Loss / GLP-1, Longevity & Peptides. He & She MD covers 7 treatment categories total and Yucca Health covers 2.

Still deciding?