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HealthRX vs PlushCare: Which Is Better?

Head-to-head comparison of HealthRX and PlushCare based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

PlushCare scores higher overall in our independent evaluation (68.3/100 vs 59.3/100), leading on trust & safety, experience, product range, reputation. HealthRX comes out ahead on value.

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HealthRX.com is a compounded-GLP-1 telehealth marketplace. It sells semaglutide at $165/mo and tirzepatide at $214/mo at every dose, and backs its program with a weight-loss money-back guarantee.

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PlushCare is a virtual primary-care membership service that layers weight-loss visits and branded GLP-1 prescriptions onto its core telehealth offering, rather than running a dedicated compounded-GLP-1 program.

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Score Breakdown

DimensionHealthRXPlushCare
Overall Score59.3/10068.3/100 ✓
Trust & Safety30%55/10078/100 ✓
Value25%78/100 ✓62/100
Experience20%60/10062/100 ✓
Product Range15%45/10065/100 ✓
Reputation10%45/10072/100 ✓

At a Glance

Founded20232014
Headquarters—San Francisco, CA
Publicly tradedNoNo
Treatment categories12
Treatments listed23
Starting price$99/mo$20/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHealthRXPlushCare
Weight Loss / GLP-1$99–$165
Compounded Semaglutide
$650–$1100
Branded GLP-1 Prescription (Wegovy, Saxenda)

HealthRX

+Flat pricing at every dose: semaglutide $165/mo ($149 first month) and tirzepatide $214/mo ($193 first month); about $99/mo semaglutide on a 12-month plan
+Physician review within 24 hours, overnight cold-chain shipping included, and a full refund if not prescribed
+Weight-loss money-back guarantee (reported terms: 16+ weeks on treatment, 10% loss threshold)
−Operating company, headquarters, medical group and dispensing pharmacy are not named; terms reference only a San Diego dispute venue
−Guarantee measurement and refund mechanics are not fully published
−Thin independent review footprint for a brand active since about 2023
Read the full HealthRX review →

PlushCare

+Low $19.99/mo membership with first month free, and insurance-eligible visits as low as a $30 copay
+Accepts major insurance plans (Aetna, Cigna, Humana), broader than most single-purpose GLP-1 telehealth startups
+Physician-led primary care model covers ongoing and chronic care beyond a single weight-loss funnel
−Branded GLP-1 medication (Zepbound, Wegovy) is billed separately at the pharmacy — without insurance coverage this can run roughly $1,000+/month, dwarfing the low membership fee
−No compounded GLP-1 option, so cash-pay patients without drug coverage face full retail brand pricing
−Trustpilot pattern of unexpected recurring membership charges and difficulty cancelling
Read the full PlushCare review →

HealthRX vs PlushCare — FAQ

Is HealthRX better than PlushCare?

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PlushCare scores higher overall in our independent evaluation (68.3/100 vs 59.3/100), leading on trust & safety, experience, product range, reputation. HealthRX comes out ahead on value.

Is HealthRX or PlushCare cheaper?

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PlushCare has the lower starting price (from $20/mo vs $99/mo for HealthRX). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do HealthRX and PlushCare both offer?

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Both platforms treat Weight Loss / GLP-1. HealthRX covers 1 treatment category total and PlushCare covers 2.

Still deciding?

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