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HealthRX vs ProlongMD: Which Is Better?

Head-to-head comparison of HealthRX and ProlongMD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 59.3/100), leading on product range. HealthRX comes out ahead on trust & safety, value, experience.

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HealthRX.com is a compounded-GLP-1 telehealth marketplace. It sells semaglutide at $165/mo and tirzepatide at $214/mo at every dose, and backs its program with a weight-loss money-back guarantee.

Visit HealthRX
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Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD

Score Breakdown

DimensionHealthRXProlongMD
Overall Score59.3/10060.1/100 ✓
Trust & Safety30%55/100 ✓52/100
Value25%78/100 ✓74/100
Experience20%60/100 ✓55/100
Product Range15%45/10070/100 ✓
Reputation10%45/10045/100

At a Glance

Founded20232025
Headquarters—Phoenix, AZ
Publicly tradedNoNo
Treatment categories18
Treatments listed213
Starting price$99/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHealthRXProlongMD
Weight Loss / GLP-1$99–$165
Compounded Semaglutide
$99–$119
Compounded Semaglutide/B12

HealthRX

+Flat pricing at every dose: semaglutide $165/mo ($149 first month) and tirzepatide $214/mo ($193 first month); about $99/mo semaglutide on a 12-month plan
+Physician review within 24 hours, overnight cold-chain shipping included, and a full refund if not prescribed
+Weight-loss money-back guarantee (reported terms: 16+ weeks on treatment, 10% loss threshold)
−Operating company, headquarters, medical group and dispensing pharmacy are not named; terms reference only a San Diego dispute venue
−Guarantee measurement and refund mechanics are not fully published
−Thin independent review footprint for a brand active since about 2023
Read the full HealthRX review →

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

HealthRX vs ProlongMD — FAQ

Is HealthRX better than ProlongMD?

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ProlongMD scores higher overall in our independent evaluation (60.1/100 vs 59.3/100), leading on product range. HealthRX comes out ahead on trust & safety, value, experience.

Is HealthRX or ProlongMD cheaper?

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ProlongMD has the lower starting price (from $25/mo vs $99/mo for HealthRX). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do HealthRX and ProlongMD both offer?

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Both platforms treat Weight Loss / GLP-1. HealthRX covers 1 treatment category total and ProlongMD covers 8.

Still deciding?

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