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Healthspan vs ProlongMD: Which Is Better?

Head-to-head comparison of Healthspan and ProlongMD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Healthspan scores higher overall in our independent evaluation (71.3/100 vs 60.1/100), leading on trust & safety, experience, product range, reputation. ProlongMD comes out ahead on value.

Healthspan is a Santa Monica-based longevity clinic built around clinician-guided rapamycin protocols, with add-on hormone, metabolic and brand-name GLP-1 care under a $99/mo membership.

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Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

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Score Breakdown

DimensionHealthspanProlongMD
Overall Score71.3/100 ✓60.1/100
Trust & Safety30%72/100 ✓52/100
Value25%68/10074/100 ✓
Experience20%72/100 ✓55/100
Product Range15%74/100 ✓70/100
Reputation10%72/100 ✓45/100

At a Glance

Founded20192025
HeadquartersSanta Monica, CAPhoenix, AZ
Publicly tradedNoNo
Treatment categories78
Treatments listed1413
Starting price$25/mo$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHealthspanProlongMD
Longevity & Peptides$25
Acarbose
$179
Sermorelin
Weight Loss / GLP-1$248–$398
Wegovy Pill with Ongoing Care
$99–$119
Compounded Semaglutide/B12
Hormone Therapy$64
Testosterone Topical Cream
$89–$119
Testosterone Cypionate (200 mg/mL)
Men's Health$60
Enclomiphene
$129–$159
Enclomiphene 25 mg
Women's Health$32
Micronized Progesterone
$33
Progesterone (oral)
Hair Loss—$25
Oral Finasteride 5 mg

Healthspan

+Deepest rapamycin-centered longevity formulary we track: oral and topical rapamycin, SGLT2 inhibitors, metformin, acarbose, LDN and methylene blue
+Low entry pricing for core longevity drugs (rapamycin from $64/mo, metformin $27, acarbose $25), shown on the homepage
+Strong patient sentiment: 4.8/5 across ~402 Trustpilot reviews, with a founder who responds personally to negative reviews
−Brand-name GLP-1s require the $99+/mo membership on top of the medication cost ($299/mo Zepbound, $149/mo Wegovy pill)
−Longevity uses of rapamycin, SGLT2 inhibitors and metformin are off-label, and headline claims (e.g., an 8-year average biological-age reduction) are self-reported
−Dispensing pharmacy and medical group are not named on the public site
Read the full Healthspan review →

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee
+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs
+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits
−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form
−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)
−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text
Read the full ProlongMD review →

Healthspan vs ProlongMD — FAQ

Is Healthspan better than ProlongMD?

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Healthspan scores higher overall in our independent evaluation (71.3/100 vs 60.1/100), leading on trust & safety, experience, product range, reputation. ProlongMD comes out ahead on value.

Is Healthspan or ProlongMD cheaper?

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Their entry prices are similar — both start around $25/mo. Real cost depends on the specific treatment: compare the pricing tables on each review, since inclusions like consults, labs, and shipping differ.

What do Healthspan and ProlongMD both offer?

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Both platforms treat Longevity & Peptides, Weight Loss / GLP-1, Hormone Therapy, Men's Health, Women's Health, Hair Loss. Healthspan covers 7 treatment categories total and ProlongMD covers 8.

Still deciding?