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Healthspan vs System Labs: Which Is Better?

Head-to-head comparison of Healthspan and System Labs based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Healthspan scores higher overall in our independent evaluation (71.3/100 vs 56.4/100), leading on trust & safety, experience, product range, reputation.

Healthspan is a Santa Monica-based longevity clinic built around clinician-guided rapamycin protocols, with add-on hormone, metabolic and brand-name GLP-1 care under a $99/mo membership.

Visit Healthspan

System Labs is a San Francisco-based telehealth service prescribing compounded NAD+, sermorelin, glutathione and MIC-B12, with half-price first months.

Visit System Labs

Score Breakdown

DimensionHealthspanSystem Labs
Overall Score71.3/100 ✓56.4/100
Trust & Safety30%72/100 ✓52/100
Value25%68/10068/100
Experience20%72/100 ✓55/100
Product Range15%74/100 ✓55/100
Reputation10%72/100 ✓45/100

At a Glance

Founded2019—
HeadquartersSanta Monica, CASan Francisco, CA
Publicly tradedNoNo
Treatment categories71
Treatments listed146
Starting price$25/mo$89/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHealthspanSystem Labs
Longevity & Peptides$25
Acarbose
$89
MIC+B12 Injection

Healthspan

+Deepest rapamycin-centered longevity formulary we track: oral and topical rapamycin, SGLT2 inhibitors, metformin, acarbose, LDN and methylene blue
+Low entry pricing for core longevity drugs (rapamycin from $64/mo, metformin $27, acarbose $25), shown on the homepage
+Strong patient sentiment: 4.8/5 across ~402 Trustpilot reviews, with a founder who responds personally to negative reviews
−Brand-name GLP-1s require the $99+/mo membership on top of the medication cost ($299/mo Zepbound, $149/mo Wegovy pill)
−Longevity uses of rapamycin, SGLT2 inhibitors and metformin are off-label, and headline claims (e.g., an 8-year average biological-age reduction) are self-reported
−Dispensing pharmacy and medical group are not named on the public site
Read the full Healthspan review →

System Labs

+Every price is posted on the site, including a first-month discount of roughly 40–50%
+Names its main compounding pharmacy (The Pharmacy Hub, Miami) and three board-certified physician advisors
+Both injectable and non-injectable options (NAD+ nasal spray, oral sermorelin)
−Trustpilot removed its business profile for guideline violations, so there is no independent review base
−'20k+ patients' claim is unverified; founding date and company history are not disclosed
−All sales are final once shipped; terms impose binding arbitration and a class-action waiver
Read the full System Labs review →

Healthspan vs System Labs — FAQ

Is Healthspan better than System Labs?

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Healthspan scores higher overall in our independent evaluation (71.3/100 vs 56.4/100), leading on trust & safety, experience, product range, reputation.

Is Healthspan or System Labs cheaper?

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Healthspan has the lower starting price (from $25/mo vs $89/mo for System Labs). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Healthspan and System Labs both offer?

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Both platforms treat Longevity & Peptides. Healthspan covers 7 treatment categories total and System Labs covers 1.

Still deciding?