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Healthspan vs Twentyeight Health: Which Is Better?

Head-to-head comparison of Healthspan and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 71.3/100), leading on trust & safety, value. Healthspan comes out ahead on product range, reputation.

71

Healthspan is a Santa Monica-based longevity clinic built around clinician-guided rapamycin protocols, with add-on hormone, metabolic and brand-name GLP-1 care under a $99/mo membership.

Visit Healthspan
75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionHealthspanTwentyeight Health
Overall Score71.3/10075/100 ✓
Trust & Safety30%72/10076/100 ✓
Value25%68/10080/100 ✓
Experience20%72/10072/100
Product Range15%74/100 ✓72/100
Reputation10%72/100 ✓70/100

At a Glance

Founded20192018
HeadquartersSanta Monica, CABrooklyn, NY
Publicly tradedNoNo
Treatment categories74
Treatments listed147
Starting price$25/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHealthspanTwentyeight Health
Weight Loss / GLP-1$248–$398
Wegovy Pill with Ongoing Care
—
Women's Health$32
Micronized Progesterone
$15–$19.99
Complete Care Membership
Dermatology——

Healthspan

+Deepest rapamycin-centered longevity formulary we track: oral and topical rapamycin, SGLT2 inhibitors, metformin, acarbose, LDN and methylene blue
+Low entry pricing for core longevity drugs (rapamycin from $64/mo, metformin $27, acarbose $25), shown on the homepage
+Strong patient sentiment: 4.8/5 across ~402 Trustpilot reviews, with a founder who responds personally to negative reviews
−Brand-name GLP-1s require the $99+/mo membership on top of the medication cost ($299/mo Zepbound, $149/mo Wegovy pill)
−Longevity uses of rapamycin, SGLT2 inhibitors and metformin are off-label, and headline claims (e.g., an 8-year average biological-age reduction) are self-reported
−Dispensing pharmacy and medical group are not named on the public site
Read the full Healthspan review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

Healthspan vs Twentyeight Health — FAQ

Is Healthspan better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 71.3/100), leading on trust & safety, value. Healthspan comes out ahead on product range, reputation.

Is Healthspan or Twentyeight Health cheaper?

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Twentyeight Health has the lower starting price (from $15/mo vs $25/mo for Healthspan). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do Healthspan and Twentyeight Health both offer?

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Both platforms treat Weight Loss / GLP-1, Women's Health, Dermatology. Healthspan covers 7 treatment categories total and Twentyeight Health covers 4.

Still deciding?

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