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HumeCare+ vs Twentyeight Health: Which Is Better?

Head-to-head comparison of HumeCare+ and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 54.2/100), leading on trust & safety, value, experience, product range, reputation.

54
HumeCare+
Below Average

HumeCare+ is the GLP-1 weight-loss program from smart-scale maker Hume Health. It bundles clinician-prescribed GLP-1 medication with a Hume Pod body-composition scale and app tracking, starting at $199/mo.

Visit HumeCare+
75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionHumeCare+Twentyeight Health
Overall Score54.2/10075/100 ✓
Trust & Safety30%52/10076/100 ✓
Value25%60/10080/100 ✓
Experience20%58/10072/100 ✓
Product Range15%50/10072/100 ✓
Reputation10%45/10070/100 ✓

At a Glance

Founded—2018
HeadquartersWilmington, DEBrooklyn, NY
Publicly tradedNoNo
Treatment categories14
Treatments listed27
Starting price$199/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryHumeCare+Twentyeight Health
Weight Loss / GLP-1$199
HumeCare+ Compounded Semaglutide Protocol
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HumeCare+

+Includes a Hume Pod body-composition scale (listed at $352) and monthly scans, so patients can track fat versus lean-mass change during GLP-1 treatment
+Protocol adds glycine, B12 and B6 aimed at muscle preservation and tolerability
+Advertises a refund if the patient does not lose 10% of body weight within 6 months (terms apply); FSA/HSA eligible
−Parent Hume Health holds a BBB F rating with 348 complaints closed in three years and a 3.5/5 Trustpilot score, mostly about refunds, device accuracy and support
−The prescribing medical group, the dispensing pharmacy and the state list are not published, and full pricing only appears after intake
−3-month minimum commitment; $199/mo headline requires a $100 welcome credit
Read the full HumeCare+ review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

HumeCare+ vs Twentyeight Health — FAQ

Is HumeCare+ better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 54.2/100), leading on trust & safety, value, experience, product range, reputation.

Is HumeCare+ or Twentyeight Health cheaper?

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Twentyeight Health has the lower starting price (from $15/mo vs $199/mo for HumeCare+). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do HumeCare+ and Twentyeight Health both offer?

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Both platforms treat Weight Loss / GLP-1. HumeCare+ covers 1 treatment category total and Twentyeight Health covers 4.

Still deciding?

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