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IVY RX vs Twentyeight Health: Which Is Better?

Head-to-head comparison of IVY RX and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 64/100), leading on trust & safety, value, experience, product range, reputation.

64
IVY RX
Fair

IVY RX is a Miami-based cash-pay telehealth platform, founded by a pharmacist in 2023, selling compounded GLP-1 injections, microdoses and oral melts alongside NAD+, sermorelin, glutathione and B12 injections.

Visit IVY RX
75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

Visit Twentyeight Health

Score Breakdown

DimensionIVY RXTwentyeight Health
Overall Score64/10075/100 ✓
Trust & Safety30%55/10076/100 ✓
Value25%68/10080/100 ✓
Experience20%70/10072/100 ✓
Product Range15%70/10072/100 ✓
Reputation10%60/10070/100 ✓

At a Glance

Founded20232018
HeadquartersMiami, FLBrooklyn, NY
Publicly tradedNoNo
Treatment categories24
Treatments listed107
Starting price$90/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryIVY RXTwentyeight Health
Weight Loss / GLP-1$90
Metformin
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IVY RX

+Large, positive Trustpilot base (4.7/5 across 7,300+ reviews) and replies to 91% of negative reviews
+Multiple GLP-1 formats (weekly injection, microdose, daily oral melts) plus branded Ozempic and Mounjaro
+Broad longevity menu (NAD+, sermorelin, glutathione, MIC-B12) with prices published before intake
−No lab work required before GLP-1 prescribing
−Markets '503B/USP <797>' sourcing, but a reviewer's order shipped from a 503A pharmacy
−BBB rating of C+ with 18 complaints over refill delays and billing after cancellation; refund policy is restrictive
Read the full IVY RX review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

IVY RX vs Twentyeight Health — FAQ

Is IVY RX better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 64/100), leading on trust & safety, value, experience, product range, reputation.

Is IVY RX or Twentyeight Health cheaper?

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Twentyeight Health has the lower starting price (from $15/mo vs $90/mo for IVY RX). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do IVY RX and Twentyeight Health both offer?

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Both platforms treat Weight Loss / GLP-1. IVY RX covers 2 treatment categories total and Twentyeight Health covers 4.

Still deciding?

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