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JRNYS vs ProlongMD: Which Is Better?

Head-to-head comparison of JRNYS and ProlongMD based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

JRNYS scores higher overall in our independent evaluation (62.8/100 vs 60.1/100), leading on trust & safety, experience, product range, reputation. ProlongMD comes out ahead on value. ProlongMD has the lower entry price (from $25/mo vs $89/mo), so the better value depends on which treatment you need.

JRNYS

Fair

JRNYS is an Austin-based, physician-founded weight-loss membership. It prescribes branded and compounded GLP-1s, sexual-health drugs and NAD+/glutathione, with tiered coaching memberships from $89 to $169/mo.

Visit JRNYS

ProlongMD

Fair

Small, veteran-owned cash-pay telehealth practice offering compounded GLP-1s, TRT, enclomiphene, women's hormones, ED, hair loss and peptides after a $79 video consult.

Visit ProlongMD

Score Breakdown

Dimension	JRNYS	ProlongMD
Overall Score	62.8/100 ✓	60.1/100
Trust & Safety30%	64/100 ✓	52/100
Value25%	55/100	74/100 ✓
Experience20%	66/100 ✓	55/100
Product Range15%	72/100 ✓	70/100
Reputation10%	58/100 ✓	45/100

At a Glance

Founded	2022	2025
Headquarters	Austin, TX	Phoenix, AZ
Publicly traded	No	No
Treatment categories	3	8
Treatments listed	7	13
Starting price	$89/mo	$25/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

Category	JRNYS	ProlongMD
Weight Loss / GLP-1	$89–$169 Weight Loss Membership (Basic / Tier I / Tier II)	$99–$119 Compounded Semaglutide/B12
Sexual Health	—	$75 Tadalafil 24 mg
Longevity & Peptides	$149 Glutathione	$179 Sermorelin

JRNYS

+Named physician founder and CMO (Dr. Henry Legere, Columbia MD, Harvard fellowship)

+Supports both insurance-covered branded GLP-1s and cash-pay compounded semaglutide/tirzepatide

+Coaching built into membership, with one-on-one sessions every six weeks (Tier I) or weekly (Tier II)

−Compounded GLP-1 prices are not published and are only quoted after the provider consult

−The $89–169/mo membership is billed on top of medication, pushing all-in cash-pay cost above flat-fee competitors

−BBB rating of C with 20 complaints closed in the past three years

Read the full JRNYS review →

ProlongMD

+Low published prices: compounded semaglutide/B12 from $99/mo and tirzepatide/B12 from $149/mo, with no membership fee

+$79 video consult is credited toward the first treatment purchase, and a written price-match policy covers comparable injectable programs

+Names its prescribing clinicians (two physicians, two nurse practitioners) and runs synchronous video visits

−Sells BPC-157/TB-500 and GHK-Cu/BPC-157/KPV/TB-500 'peptide blends', compounds the FDA has flagged for safety concerns and which have no approved drug form

−Dispensing pharmacies are not named, and the states served are not published (visible reviews come only from TX and CO)

−Very new (LLC formed August 2025) with no independent review footprint; several on-site star ratings have no review text

Read the full ProlongMD review →

JRNYS vs ProlongMD — FAQ

Is JRNYS better than ProlongMD?

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Is JRNYS or ProlongMD cheaper?

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ProlongMD has the lower starting price (from $25/mo vs $89/mo for JRNYS). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do JRNYS and ProlongMD both offer?

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Both platforms treat Weight Loss / GLP-1, Sexual Health, Longevity & Peptides. JRNYS covers 3 treatment categories total and ProlongMD covers 8.

Still deciding?

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