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JRNYS vs System Labs: Which Is Better?

Head-to-head comparison of JRNYS and System Labs based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

JRNYS scores higher overall in our independent evaluation (62.8/100 vs 56.4/100), leading on trust & safety, experience, product range, reputation. System Labs comes out ahead on value.

63
JRNYS
Fair

JRNYS is an Austin-based, physician-founded weight-loss membership. It prescribes branded and compounded GLP-1s, sexual-health drugs and NAD+/glutathione, with tiered coaching memberships from $89 to $169/mo.

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56

System Labs is a San Francisco-based telehealth service prescribing compounded NAD+, sermorelin, glutathione and MIC-B12, with half-price first months.

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Score Breakdown

DimensionJRNYSSystem Labs
Overall Score62.8/100 ✓56.4/100
Trust & Safety30%64/100 ✓52/100
Value25%55/10068/100 ✓
Experience20%66/100 ✓55/100
Product Range15%72/100 ✓55/100
Reputation10%58/100 ✓45/100

At a Glance

Founded2022—
HeadquartersAustin, TXSan Francisco, CA
Publicly tradedNoNo
Treatment categories31
Treatments listed76
Starting price$89/mo$89/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryJRNYSSystem Labs
Longevity & Peptides$149
Glutathione
$89
MIC+B12 Injection

JRNYS

+Named physician founder and CMO (Dr. Henry Legere, Columbia MD, Harvard fellowship)
+Supports both insurance-covered branded GLP-1s and cash-pay compounded semaglutide/tirzepatide
+Coaching built into membership, with one-on-one sessions every six weeks (Tier I) or weekly (Tier II)
−Compounded GLP-1 prices are not published and are only quoted after the provider consult
−The $89–169/mo membership is billed on top of medication, pushing all-in cash-pay cost above flat-fee competitors
−BBB rating of C with 20 complaints closed in the past three years
Read the full JRNYS review →

System Labs

+Every price is posted on the site, including a first-month discount of roughly 40–50%
+Names its main compounding pharmacy (The Pharmacy Hub, Miami) and three board-certified physician advisors
+Both injectable and non-injectable options (NAD+ nasal spray, oral sermorelin)
−Trustpilot removed its business profile for guideline violations, so there is no independent review base
−'20k+ patients' claim is unverified; founding date and company history are not disclosed
−All sales are final once shipped; terms impose binding arbitration and a class-action waiver
Read the full System Labs review →

JRNYS vs System Labs — FAQ

Is JRNYS better than System Labs?

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JRNYS scores higher overall in our independent evaluation (62.8/100 vs 56.4/100), leading on trust & safety, experience, product range, reputation. System Labs comes out ahead on value.

Is JRNYS or System Labs cheaper?

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Their entry prices are similar — both start around $89/mo. Real cost depends on the specific treatment: compare the pricing tables on each review, since inclusions like consults, labs, and shipping differ.

What do JRNYS and System Labs both offer?

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Both platforms treat Longevity & Peptides. JRNYS covers 3 treatment categories total and System Labs covers 1.

Still deciding?

JRNYS alternativesSystem Labs alternativesTake the Match Quiz