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JRNYS vs Twentyeight Health: Which Is Better?

Head-to-head comparison of JRNYS and Twentyeight Health based on our independent scoring across trust, value, experience, product range, and reputation — plus real pricing for the treatments they both offer.

Our Verdict

Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 62.8/100), leading on trust & safety, value, experience, reputation.

63
JRNYS
Fair

JRNYS is an Austin-based, physician-founded weight-loss membership. It prescribes branded and compounded GLP-1s, sexual-health drugs and NAD+/glutathione, with tiered coaching memberships from $89 to $169/mo.

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75

Brooklyn-based women's telehealth service covering birth control, emergency contraception, UTI/BV/yeast and herpes treatment, prescription skincare and branded GLP-1s under a $19.99/mo membership ($0 in-network).

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Score Breakdown

DimensionJRNYSTwentyeight Health
Overall Score62.8/10075/100 ✓
Trust & Safety30%64/10076/100 ✓
Value25%55/10080/100 ✓
Experience20%66/10072/100 ✓
Product Range15%72/10072/100
Reputation10%58/10070/100 ✓

At a Glance

Founded20222018
HeadquartersAustin, TXBrooklyn, NY
Publicly tradedNoNo
Treatment categories34
Treatments listed77
Starting price$89/mo$15/mo

Pricing Where They Compete

Prices shown are based on our most recent research and may not reflect current pricing. Telehealth providers update their pricing frequently. Always verify pricing directly with the provider before purchasing.

CategoryJRNYSTwentyeight Health
Weight Loss / GLP-1$89–$169
Weight Loss Membership (Basic / Tier I / Tier II)
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Sexual Health——

JRNYS

+Named physician founder and CMO (Dr. Henry Legere, Columbia MD, Harvard fellowship)
+Supports both insurance-covered branded GLP-1s and cash-pay compounded semaglutide/tirzepatide
+Coaching built into membership, with one-on-one sessions every six weeks (Tier I) or weekly (Tier II)
−Compounded GLP-1 prices are not published and are only quoted after the provider consult
−The $89–169/mo membership is billed on top of medication, pushing all-in cash-pay cost above flat-fee competitors
−BBB rating of C with 20 complaints closed in the past three years
Read the full JRNYS review →

Twentyeight Health

+Low entry cost: $19.99/mo membership ($0 when in-network), birth control from $16/pack cash and often $0 with insurance
+Accepts most commercial insurance and Medicaid in multiple states, which few D2C telehealth brands do
+One membership covers contraception, EC, UTI/BV/yeast, herpes, skincare and weight care, and urgent-care prescriptions are ready for pickup in 4–6 hours
−Medications are billed separately from the membership, which some reviewers say caused unexpected charges
−Weight care (branded Wegovy/Zepbound only) is limited to about 22 states, and skincare to a subset of states
−21% of Trustpilot reviews are 1-star, citing billing discrepancies and support communication problems
Read the full Twentyeight Health review →

JRNYS vs Twentyeight Health — FAQ

Is JRNYS better than Twentyeight Health?

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Twentyeight Health scores higher overall in our independent evaluation (75/100 vs 62.8/100), leading on trust & safety, value, experience, reputation.

Is JRNYS or Twentyeight Health cheaper?

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Twentyeight Health has the lower starting price (from $15/mo vs $89/mo for JRNYS). Starting prices are for the cheapest treatment each offers — compare the specific treatment you need, and check what each price includes.

What do JRNYS and Twentyeight Health both offer?

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Both platforms treat Weight Loss / GLP-1, Sexual Health. JRNYS covers 3 treatment categories total and Twentyeight Health covers 4.

Still deciding?

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